# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA635637 | ADME | Activity relative to saturating aminopterine at 100 uM against CCRF-CEM Folyl-polyglutamate synthetase | 9 | ALA1126566 | cell-based format | Scientific Literature | ||
2. | ALA665043 | Binding | Tested for inhibition against Pneumocystis carinii DHFR (dihydrofolate reductase) | Pneumocystis carinii | 1 | ALA1126566 | single protein format | Scientific Literature | |
3. | ALA667327 | Binding | Inhibitory activity of Dihydrofolate reductase in L1210 cells | 9 | ALA1126566 | cell-based format | Scientific Literature | ||
4. | ALA884431 | Binding | Tested for inhibition against rat liver DHFR (dihydrofolate reductase) | 1 | ALA1126566 | assay format | Scientific Literature | ||
5. | ALA677118 | Binding | Percent inhibition of Folyl-polyglutamate synthase from CCRF-CEM cells | Homo sapiens | 6 | ALA1126566 | cell-based format | Scientific Literature | |
6. | ALA677120 | Binding | Michaelis-Menten constant was determined against CCRF-CEM Folyl-polyglutamate synthase | Homo sapiens | 1 | ALA1126566 | assay format | Scientific Literature | |
7. | ALA682275 | Binding | Specific activity of L1210 Folyl-polyglutamate synthase | 4 | ALA1126566 | single protein format | Scientific Literature | ||
8. | ALA695279 | Functional | Tested for the ability to inhibit growth in vitro against HL60 | Homo sapiens | 9 | ALA1126566 | cell-based format | Scientific Literature | |
9. | ALA707443 | Functional | Tested for transport into L1210 cells measured as cell influx | Mus musculus | 9 | ALA1126566 | cell-based format | Scientific Literature | |
10. | ALA701951 | Functional | Tested for the ability to inhibit growth in vitro against L1210 | Mus musculus | 9 | ALA1126566 | cell-based format | Scientific Literature | |
11. | ALA852321 | ADME | Ratio of Vmax and Km against CCRF-CEM Folyl-polyglutamate synthetase | 2 | ALA1126566 | cell-based format | Scientific Literature | ||
12. | ALA1794359 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] | 25,086 | ALA1201862 | assay format | PubChem BioAssays | ||
13. | ALA1794483 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | 114,923 | ALA1201862 | assay format | PubChem BioAssays | ||
14. | ALA1794495 | Functional | PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) | 13,233 | ALA1201862 | assay format | PubChem BioAssays | ||
15. | ALA1794585 | Functional | PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) | 35,474 | ALA1201862 | assay format | PubChem BioAssays | ||
16. | ALA803797 | Functional | Tested for the ability to inhibit growth in vitro against S180 | Mus musculus | 8 | ALA1126566 | cell-based format | Scientific Literature | |
17. | ALA1738184 | Functional | PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] | Homo sapiens | 77,876 | ALA1201862 | assay format | PubChem BioAssays | |
18. | ALA744199 | Functional | Antitumor activity against E0771 mammary adenocarcinoma in mice at 100 mg/kg(5 days) was determined and tumor volume at day 10 was reported | Mus musculus | 1 | ALA1126566 | organism-based format | Scientific Literature | |
19. | ALA744200 | Functional | Antitumor activity against E0771 mammary adenocarcinoma in mice at 100 mg/kg(5 days) was determined and tumor volume at day 14 was reported | Mus musculus | 2 | ALA1126566 | organism-based format | Scientific Literature | |
20. | ALA744201 | Functional | Antitumor activity against E0771 mammary adenocarcinoma in mice at 100 mg/kg(5 days) was determined and tumor volume at day 7 was reported | Mus musculus | 1 | ALA1126566 | organism-based format | Scientific Literature |