# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3988182 | F | GSK PKIS2: Screen against O. lienalis microfilariae, single point, at 3.1uM to assess reduction in motility. Compounds were also tested for cytotoxicity against Rhesus Monkey LLCMK2 cells. A score was assigned as follows: Score 3 = Good activity, 100 % motility reduction; Score 2 = Marginal/moderate activity, 50-99% motility reduction; Score 1 = Inactive, <50% motility reduction; Score 0 = Cytotoxic. | Onchocerca lienalis | 486 | ALA3988181 | cell-based format | Published Kinase Inhibitor Set 2 | |
2. | ALA5236730 | B | Inhibition of MSK-1 (unknown origin) | Homo sapiens | 12 | ALA5236544 | single protein format | Scientific Literature |