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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4219431 Binding Displacement of cy5-conjugated 2-((1E,3E,5Z)-5-(1-(6-((4-(2-((2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)acetamido)butyl)amino)-6-oxohexyl)-3,3-dimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-1,3,3-trimethyl-3H-indol-1-ium from DDB1-fused human full length 6xHis-tagged CRBN expressed in Sf9 insect cells after 10 mins by TR-FRET assay Homo sapiens 3 ALA4219026 cell-based format Scientific Literature 2. ALA4219432 Binding Induction of cereblon-mediated GSPT1 degradation in human DF15 cells expressing ePL-tagged GSPT1 at 0.0005 to 10 uM after 4 hrs by luminometric analysis Homo sapiens 1 ALA4219026 cell-based format Scientific Literature 3. ALA4219433 Binding Induction of cereblon-mediated CK1alpha (unknown origin) degradation in at 0.0005 to 10 uM after 4 hrs by cell-based chemiluminescent assay Homo sapiens 1 ALA4219026 cell-based format Scientific Literature 4. ALA4219434 Binding Induction of cereblon-mediated ikaros degradation in human DF15 cells expressing ePL-tagged ikaros after 4 hrs by luminometric analysis Homo sapiens 3 ALA4219026 cell-based format Scientific Literature 5. ALA4219435 Binding Induction of cereblon-mediated aiolos degradation in human DF15 cells expressing ePL-tagged aiolos after 4 hrs by luminometric analysis Homo sapiens 3 ALA4219026 cell-based format Scientific Literature 6. ALA4219436 Binding Induction of cereblon-mediated ikaros degradation in human DF15 cells at 0.1 to 10 uM after 5 hrs by immunoblot analysis Homo sapiens 2 ALA4219026 cell-based format Scientific Literature 7. ALA4219437 Binding Induction of cereblon-mediated aiolos degradation in human DF15 cells at 0.1 to 10 uM after 5 hrs by immunoblot analysis Homo sapiens 2 ALA4219026 cell-based format Scientific Literature 8. ALA4219438 Binding Induction of cereblon-mediated ikaros degradation in human OPM2 cells at 0.1 to 10 uM after 5 hrs by immunoblot analysis Homo sapiens 2 ALA4219026 cell-based format Scientific Literature 9. ALA4219439 Binding Induction of cereblon-mediated aiolos degradation in human OPM2 cells at 0.1 to 10 uM after 5 hrs by immunoblot analysis Homo sapiens 2 ALA4219026 cell-based format Scientific Literature 10. ALA4396185 ADME MRT (infinity) in BALB/c mouse at 5 mg/kg, iv and measured up to 24 hrs by LC-MS/MS analysis Mus musculus 4 ALA4393715 organism-based format Scientific Literature 11. ALA4396186 Functional Antiproliferative activity against human MV411 cells measured after 168 hrs by CellTiter96 Aqueous non-radioactive cell proliferation assay Homo sapiens 18 ALA4393715 cell-based format Scientific Literature 12. ALA4396187 Functional Antiproliferative activity against human Mino cells measured after 72 hrs by CellTiter96 Aqueous non-radioactive cell proliferation assay Homo sapiens 31 ALA4393715 cell-based format Scientific Literature 13. ALA4396188 Functional Antiproliferative activity against human MM1S cells measured after 168 hrs by CellTiter96 Aqueous non-radioactive cell proliferation assay Homo sapiens 18 ALA4393715 cell-based format Scientific Literature 14. ALA4396197 ADME AUC (infinity) in BALB/c mouse at 5 mg/kg, iv and measured up to 24 hrs by LC-MS/MS analysis Mus musculus 4 ALA4393715 organism-based format Scientific Literature 15. ALA4396198 ADME Clearance in BALB/c mouse at 5 mg/kg, iv and measured up to 24 hrs by LC-MS/MS analysis Mus musculus 4 ALA4393715 organism-based format Scientific Literature 16. ALA4396199 ADME Volume of distribution at steady state in BALB/c mouse at 5 mg/kg, iv and measured up to 24 hrs by LC-MS/MS analysis Mus musculus 4 ALA4393715 organism-based format Scientific Literature 17. ALA4396200 ADME Half-life in BALB/c mouse at 5 mg/kg, iv and measured up to 24 hrs by LC-MS/MS analysis Mus musculus 4 ALA4393715 organism-based format Scientific Literature 18. ALA4396201 ADME AUC (infinity) in BALB/c mouse at 20 mg/kg, po and measured up to 24 hrs by LC-MS/MS analysis Mus musculus 4 ALA4393715 organism-based format Scientific Literature 19. ALA4396202 ADME Terminal elimination half life in BALB/c mouse at 20 mg/kg, po and measured up to 24 hrs by LC-MS/MS analysis Mus musculus 4 ALA4393715 organism-based format Scientific Literature 20. ALA4396203 ADME Tmax in BALB/c mouse at 20 mg/kg, po and measured up to 24 hrs by LC-MS/MS analysis Mus musculus 4 ALA4393715 organism-based format Scientific Literature