| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4143450 | B | Inhibition of human IDO1 assessed as reduction in kynurenine production | Homo sapiens | 5 | ALA4138229 | single protein format | Scientific Literature | |
| 2. | ALA4143452 | B | Inhibition of human IDO1 expressed in T-REx-293 cells | Homo sapiens | 1 | ALA4138229 | cell-based format | Scientific Literature | |
| 3. | ALA4143459 | B | Inhibition of TDO (unknown origin) | Homo sapiens | 2 | ALA4138229 | single protein format | Scientific Literature | |
| 4. | ALA4143460 | B | Inhibition of human TDO expressed in T-REx-293 cells | Homo sapiens | 1 | ALA4138229 | cell-based format | Scientific Literature | |
| 5. | ALA4345928 | B | Inhibition of TDO (unknown origin) | Homo sapiens | 4 | ALA4342513 | single protein format | Scientific Literature | |
| 6. | ALA4345929 | B | Inhibition of IDO1 (unknown origin) | Homo sapiens | 1 | ALA4342513 | single protein format | Scientific Literature | |
| 7. | ALA4355076 | B | Inhibition of IDO1 (unknown origin) by cell based assay | Homo sapiens | 1 | ALA4354789 | cell-based format | Scientific Literature | |
| 8. | ALA4355077 | F | Invivo inhibition of IDO1 in mouse assessed as reduction in kynurenine level in plasma relative to control | Mus musculus | 1 | ALA4354789 | organism-based format | Scientific Literature | |
| 9. | ALA4355078 | F | Antitumour activity in human B16 cells pretreated with compound followed by tumour implantation assessed as reduction in tumour size after 4 days relative to control | Homo sapiens | 1 | ALA4354789 | cell-based format | Scientific Literature | |
| 10. | ALA4360761 | B | Inhibition of human IDO1 expressed in Escherichia coli Rosetta measured after 1 hr by microplate reader analysis | Homo sapiens | 26 | ALA4359827 | assay format | Scientific Literature | |
| 11. | ALA4360762 | B | Inhibition of human TDO expressed in Escherichia coli Rosetta measured after 1 hr microplate reader analysis | Homo sapiens | 25 | ALA4359827 | assay format | Scientific Literature | |
| 12. | ALA4360763 | B | Inhibition of IDO in human HeLa cells using tryptophan as substrate measured after 48 hrs in presence of INF gamma microplate reader analysis | Homo sapiens | 25 | ALA4359827 | cell-based format | Scientific Literature | |
| 13. | ALA4360770 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | ALA4359827 | single protein format | Scientific Literature | |
| 14. | ALA4367260 | B | Inhibition of purified human IDO1 using varying levels of L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 1.5 to 15 mins by spectrophotometry-based Morrison equation analysis | Homo sapiens | 1 | ALA4364294 | single protein format | Scientific Literature | |
| 15. | ALA4367261 | B | Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins by spectrophotometric method | Homo sapiens | 87 | ALA4364294 | single protein format | Scientific Literature | |
| 16. | ALA4367262 | B | Inhibition of recombinant human IDO1 expressed in T-REx-293 cells assessed as reduction in kynurenine level measured after 16 hrs | Homo sapiens | 73 | ALA4364294 | cell-based format | Scientific Literature | |
| 17. | ALA4367264 | A | Inhibition of CYP3A4 (unknown origin) using midazolam as substrate | Homo sapiens | 32 | ALA4364294 | single protein format | Scientific Literature | |
| 18. | ALA4367265 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 32 | ALA4364294 | single protein format | Scientific Literature | |
| 19. | ALA4367266 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 32 | ALA4364294 | single protein format | Scientific Literature | |
| 20. | ALA4367267 | A | Inhibition of CYP2B6 (unknown origin) | Homo sapiens | 32 | ALA4364294 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!