| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA685802 | F | Reduction of tumor cell growth to 50% in Fostriecin analogues in HCT-8 colon cancer cell lines | Homo sapiens | 5 | ALA1135579 | cell-based format | Scientific Literature | |
| 2. | ALA705627 | F | Reduction of tumor cell growth to 50% in Fostriecin analogues in L1210 Leukemia cell lines | Mus musculus | 5 | ALA1135579 | cell-based format | Scientific Literature | |
| 3. | ALA705547 | F | Inhibitory activity against L1210 leukemia cells | Mus musculus | 1 | ALA1133252 | cell-based format | Scientific Literature | |
| 4. | ALA767489 | B | Inhibitory activity against partially purified (chicken skeletal muscle) Protein phosphatase 2A | 9 | ALA1133252 | tissue-based format | Scientific Literature | ||
| 5. | ALA804802 | B | Exogenous inhibition of Serine/threonine protein phosphatase 1 (PP1) | Homo sapiens | 11 | ALA1135579 | assay format | Scientific Literature | |
| 6. | ALA799062 | B | Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A) | 10 | ALA1135579 | single protein format | Scientific Literature | ||
| 7. | ALA816602 | B | Inhibition of topoisomerase IIin vitro through a novel, non-DNA-strandcleaving mechanism | 1 | ALA1133252 | single protein format | Scientific Literature | ||
| 8. | ALA1048608 | B | Inhibition of protein phosphatase 1 | 1 | ALA1152684 | assay format | Scientific Literature | ||
| 9. | ALA1048609 | B | Inhibition of protein phosphatase 2A | 1 | ALA1152684 | assay format | Scientific Literature | ||
| 10. | ALA1048610 | B | Selectivity for protein phosphatase 2A over protein phosphatase 1 | 1 | ALA1152684 | assay format | Scientific Literature | ||
| 11. | ALA1049420 | B | Selectivity for protein phosphatase 2A over protein phosphatase 2B | 1 | ALA1152684 | assay format | Scientific Literature | ||
| 12. | ALA1049421 | B | Selectivity for protein phosphatase 2A over protein phosphatase 5 | 1 | ALA1152684 | assay format | Scientific Literature | ||
| 13. | ALA1049422 | F | Cytotoxicity against mouse L1210 cells after 72 hrs by WST8 dye reduction assay | Mus musculus | 2 | ALA1152684 | cell-based format | Scientific Literature | |
| 14. | ALA1042468 | B | Binding affinity to cysteine-269 residue of human protein phosphatase 2A catalytic subunit at 0.6 uM after 2 hrs by MALDI-TOF MS analysis | Homo sapiens | 1 | ALA1152684 | assay format | Scientific Literature | |
| 15. | ALA1614670 | A | Volume of distribution at steady state in human after iv administration | Homo sapiens | 667 | ALA1614632 | organism-based format | Scientific Literature | |
| 16. | ALA1614671 | A | Clearance in human after iv administration | Homo sapiens | 667 | ALA1614632 | organism-based format | Scientific Literature | |
| 17. | ALA1614673 | A | Mean residence time in human after iv administration | Homo sapiens | 667 | ALA1614632 | organism-based format | Scientific Literature | |
| 18. | ALA1614674 | A | Half life in human after iv administration | Homo sapiens | 667 | ALA1614632 | organism-based format | Scientific Literature | |
| 19. | ALA3137722 | T | Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum activity 6 times the normal upper limit (N) or alkaline phosphatase serum activity of 1.7 N. Value is number of references indexed. [column 'BIOL' in source] | Homo sapiens | 1,214 | ALA3137667 | tissue-based format | Scientific Literature | |
| 20. | ALA3137723 | T | Highest frequency of moderate liver toxicity observed during clinical trials, expressed as a percentage. [column '% BIOL' in source] | Homo sapiens | 1,214 | ALA3137667 | tissue-based format | Scientific Literature |
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