| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4031957 | F | Selectivity index, ratio of GI50 for human HCC1806 cells to GI50 for human SUM185PE cells | Homo sapiens | 1 | ALA4028880 | assay format | Scientific Literature | |
| 2. | ALA4031958 | F | Selectivity index, ratio of GI50 for human MDA-MB-231 cells to GI50 for human SUM185PE cells | Homo sapiens | 1 | ALA4028880 | assay format | Scientific Literature | |
| 3. | ALA4031959 | F | Cytotoxicity against human MDA-MB-453 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method | Homo sapiens | 26 | ALA4028880 | cell-based format | Scientific Literature | |
| 4. | ALA4031960 | F | Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method | Homo sapiens | 26 | ALA4028880 | cell-based format | Scientific Literature | |
| 5. | ALA4031961 | F | Cytotoxicity against human HCC1937 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method | Homo sapiens | 26 | ALA4028880 | cell-based format | Scientific Literature | |
| 6. | ALA4031963 | F | Cytotoxicity against human BT549 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method | Homo sapiens | 26 | ALA4028880 | cell-based format | Scientific Literature | |
| 7. | ALA4031966 | F | Selectivity index, ratio of GI50 for human MDA-MB-231 cells to GI50 for human MDA-MB-453 cells | Homo sapiens | 3 | ALA4028880 | assay format | Scientific Literature | |
| 8. | ALA4031971 | F | Cytotoxicity against human SUM185PE cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method | Homo sapiens | 11 | ALA4028880 | cell-based format | Scientific Literature | |
| 9. | ALA4031972 | F | Cytotoxicity against human HCC1806 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method | Homo sapiens | 11 | ALA4028880 | cell-based format | Scientific Literature | |
| 10. | ALA4031973 | A | Cytotoxicity against rat A10 cells assessed as growth inhibition incubated for 48 to 96 hrs by SRB method | Rattus norvegicus | 11 | ALA4028880 | cell-based format | Scientific Literature | |
| 11. | ALA4031974 | F | Selectivity index, ratio of GI50 for human HCC1806 cells to GI50 for human MDA-MB-453 cells | Homo sapiens | 1 | ALA4028880 | assay format | Scientific Literature | |
| 12. | ALA4031976 | F | Cell cycle arrest in human MDA-MB-453 cells assessed as accumulation at sub-G1 phase at GI50 to LC50 incubated for 18 hrs by Krishan's reagent staining-based flow cytometric method | Homo sapiens | 3 | ALA4028880 | cell-based format | Scientific Literature | |
| 13. | ALA4031977 | B | Activation of PI3K/PDK1/AKT pathway in human MDA-MB-453 cells assessed as increase in AKT phosphorylation at Thr308 at 1 uM after 1 hr by Western blot method relative to control | Homo sapiens | 1 | ALA4028880 | cell-based format | Scientific Literature | |
| 14. | ALA4031978 | B | Inhibition of mTORC1 in human MDA-MB-453 cells assessed as decrease in mTOR phosphorylation at Ser2448 at 1 uM after 1 hr by Western blot method relative to control | Homo sapiens | 1 | ALA4028880 | cell-based format | Scientific Literature | |
| 15. | ALA4031979 | B | Activation of PI3K/PDK1/AKT pathway in human MDA-MB-453 cells assessed as increase in mTOR phosphorylation at Ser2448 at 1 uM after 6 hrs by Western blot method relative to control | Homo sapiens | 1 | ALA4028880 | cell-based format | Scientific Literature | |
| 16. | ALA4031980 | B | Inhibition of mTORC1 in human MDA-MB-453 cells assessed as decrease in S6K phosphorylation at Thr389 at 1 uM after 1 hr by Western blot method relative to control | Homo sapiens | 1 | ALA4028880 | cell-based format | Scientific Literature | |
| 17. | ALA4031981 | B | Inhibition of mTORC1 in human MDA-MB-453 cells assessed as decrease in S6 phosphorylation at Ser235/Ser236 residues at 1 uM after 1 hr by Western blot method relative to control | Homo sapiens | 1 | ALA4028880 | cell-based format | Scientific Literature | |
| 18. | ALA4031982 | B | Effect on mTORC2-mediated AKT phosphorylation at Ser473 in human MDA-MB-453 cells at 1 uM after 1 hr by Western blot method relative to control | Homo sapiens | 1 | ALA4028880 | cell-based format | Scientific Literature | |
| 19. | ALA4031984 | B | Activation of PI3K/PDK1/AKT pathway in human MDA-MB-453 cells assessed as increase in mTOR phosphorylation at Ser2448 at 1 uM after 2 hrs by Western blot method relative to control | Homo sapiens | 1 | ALA4028880 | cell-based format | Scientific Literature | |
| 20. | ALA4031986 | B | Activation of PI3K/PDK1/AKT pathway in human MDA-MB-453 cells assessed as increase in AKT phosphorylation at Thr308 at 1 uM after 2 hrs by Western blot method relative to control | Homo sapiens | 1 | ALA4028880 | cell-based format | Scientific Literature |
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