# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4039787 | A | Cytotoxicity against human Huh7.5.1 cells assessed as reduction in cell viability by measuring relative luminescence unit at 10 uM after 48 hrs by ATPlite assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA4039788 | U | Selectivity index, ratio of CC50 for human Huh7.5.1 cells to EC50 for HCV genotype 2a JFH-1 infected in human Huh7.5.1 cells | 58 | cell-based format | Scientific Literature | |||
3. | ALA4039789 | F | Antiviral activity against HCV genotype 2a JFH-1 infected in human Huh7.5.1 cells assessed as inhibition of viral replication by measuring relative luminescence unit at 10 uM after 48 hrs by luciferase reporter assay relative to control | Hepacivirus hominis | 4 | cell-based format | Scientific Literature | ||
4. | ALA4039790 | F | Antiviral activity against murine leukemia virus pseudoparticle infected in human Huh7.5.1 cells assessed as inhibition of viral entry by measuring relative luminescence unit at 10 uM after 48 hrs by luciferase reporter gene assay relative to control | Murine leukemia virus | 4 | cell-based format | Scientific Literature | ||
5. | ALA4039791 | F | Antiviral activity against vesicular stomatitis virus pseudoparticle harboring VSV G protein infected in human Huh7.5.1 cells assessed as inhibition of viral entry by measuring relative luminescence unit at 10 uM treated for 4 hrs measured after 48 hrs by luciferase reporter gene assay relative to control | Vesicular stomatitis virus | 4 | cell-based format | Scientific Literature | ||
6. | ALA4039792 | F | Antiviral activity against HCV genotype 2a JFH-1 infected in human Huh7.5.1 cells assessed as inhibition of viral replication after 48 hrs by luciferase reporter gene assay | Hepacivirus hominis | 59 | cell-based format | Scientific Literature | ||
7. | ALA4039793 | A | Cytotoxicity against human Huh7.5.1 cells assessed as reduction in cell viability after 48 hrs by ATPlite assay | Homo sapiens | 58 | cell-based format | Scientific Literature | ||
8. | ALA4039804 | P | Kinetic solubility of the compound in pH 7.4 phosphate buffer | 58 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA4039805 | P | Permeability of the compound by PAMPA | 58 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA4039806 | A | Half life in rat liver microsomes at 37 degC in presence of NADPH by LC-MS/MS method | Rattus norvegicus | 58 | assay format | Scientific Literature | ||
11. | ALA4039856 | F | Antiviral activity against single-round infectious defective HCVsc genotype 2a infected in human Huh7.5.1 cells assessed as inhibition of viral replication by measuring relative luminescence unit at 10 uM after 48 hrs by luciferase reporter gene assay | Hepacivirus hominis | 4 | cell-based format | Scientific Literature | ||
12. | ALA4039857 | F | Antiviral activity against HCV genotype 1b in HCV replicon cells assessed as reduction in viral RNA replication by measuring relative luminescence unit at 10 uM after 48 hrs by luciferase reporter gene assay relative to control | Hepacivirus hominis | 4 | cell-based format | Scientific Literature | ||
13. | ALA4039858 | F | Antiviral activity against Hepatitis C virus pseudoparticle genotype 1a harboring HCV envelope glycoprotein infected in human Huh7.5.1 cells assessed as inhibition of viral entry by measuring relative luminescence unit at 10 uM treated for 4 hrs measured after 48 hrs by luciferase reporter gene assay assay relative to control | Hepacivirus hominis | 4 | cell-based format | Scientific Literature | ||
14. | ALA4039859 | F | Antiviral activity against Hepatitis C virus pseudoparticle genotype 1b harboring HCV envelope glycoprotein infected in human Huh7.5.1 cells assessed as inhibition of viral entry by measuring relative luminescence unit at 10 uM after 48 hrs by luciferase reporter gene assay relative to control | Hepacivirus hominis | 4 | cell-based format | Scientific Literature |