# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA856036 | Functional | IC50 evaluated by measuring contraction and relaxation of guinea pig bladder strips with KCl and glibenclamide respectively | Cavia porcellus | 77 | ALA1129399 | assay format | Scientific Literature | |
2. | ALA701213 | Functional | Evaluated for K-ATP activity in terms of change in membrane potential through guinea pig bladder assay | Cavia porcellus | 68 | ALA1148324 | cell membrane format | Scientific Literature | |
3. | ALA701216 | Functional | Evaluated for K-ATP activity in terms of stable twitch response through field-stimulated landrace pig detrusor assay | Sus scrofa | 36 | ALA1148324 | assay format | Scientific Literature | |
4. | ALA699663 | Functional | Evaluated for K-ATP activity as in vitro bladder relaxation in spontaneous Landrace pig detrusor strips (SLPD) | Sus scrofa | 6 | ALA1148324 | assay format | Scientific Literature | |
5. | ALA700931 | Functional | In vitro ATP-sensitive potassium channel (KATP) activity in cells expressing human KATP channels Kir6.2 and sulfonylurea receptor 2B | Homo sapiens | 1 | ALA1148468 | assay format | Scientific Literature | |
6. | ALA778525 | Functional | In vivo concentration required for the reduction of mean arterial pressure in anesthetized obstructed male rat, administered intravenously at a dose of 50 nM/Kg | Rattus norvegicus | 2 | ALA1136389 | organism-based format | Scientific Literature | |
7. | ALA776996 | Functional | Compound was evaluated in vivo for the effective dose that cause a 20% drop in MAP normotensive rat after oral administration | Rattus norvegicus | 4 | ALA1132985 | organism-based format | Scientific Literature | |
8. | ALA777591 | Functional | Effective dose in vivo for reduction in MAP in normotensive rat model after oral administration | Rattus norvegicus | 3 | ALA1132984 | organism-based format | Scientific Literature | |
9. | ALA783034 | Functional | In vivo concentration required for the inhibition of unstable contraction in anesthetized obstructed male rat, administered intravenously at a dose of 30 nM/Kg | Rattus norvegicus | 3 | ALA1136389 | organism-based format | Scientific Literature | |
10. | ALA785427 | Functional | Compound was evaluated in vivo for the effective dose that cause a 50% reduction in frequency of spontaneous bladder contraction in the rat hypertrophied model after oral administration | Rattus norvegicus | 8 | ALA1132985 | organism-based format | Scientific Literature | |
11. | ALA780594 | Functional | Effective dose in vivo for reduction in the frequency of spontaneous bladder contractions in the rat oral administration | Rattus norvegicus | 3 | ALA1132984 | organism-based format | Scientific Literature | |
12. | ALA779563 | Functional | In vitro inhibitory concentration that relaxed KCL induced contraction in rat detrusor strip by 50% | Rattus norvegicus | 77 | ALA1132985 | organism-based format | Scientific Literature | |
13. | ALA779564 | Functional | In vitro inhibitory concentration that relaxes KCL induced contraction in rat detrusor strips by 50% | Rattus norvegicus | 76 | ALA1132984 | organism-based format | Scientific Literature | |
14. | ALA849847 | Functional | Selectivity ratio for the reduction of mean arterial pressure to that of unstable concentration in anesthetized obstructed male rat | 3 | ALA1136389 | tissue-based format | Scientific Literature | ||
15. | ALA846990 | Functional | Selectivity expressed as the ratio of pEC50 (SLPD) and pEC50 (FSLPD) | 6 | ALA1148324 | assay format | Scientific Literature | ||
16. | ALA848710 | Functional | Selectivity ratio of MAP ED20/bladder ED50 | 3 | ALA1132984 | assay format | Scientific Literature | ||
17. | ALA848711 | Functional | Selectivity ratio of MAP ED20/bladder ED50 | 4 | ALA1132985 | assay format | Scientific Literature | ||
18. | ALA762565 | Functional | In vitro functional potassium channel opening activity in tissue strips from Landrace pig bladders(LPD) | Sus scrofa | 1 | ALA1148468 | assay format | Scientific Literature | |
19. | ALA767695 | Functional | In vivo inhibion of pyruvate dehydrogenase kinase, increased oxidation of lactate | Homo sapiens | 8 | ALA1132309 | organism-based format | Scientific Literature | |
20. | ALA767697 | Binding | In vitro inhibitory activity against Pyruvate dehydrogenase kinase by primary enzymatic assay | Sus scrofa | 18 | ALA1132309 | protein format | Scientific Literature |