| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4043739 | B | Binding affinity to human telomeric 23 G-quadruplex DNA assessed as change in melting temperature at 10 molequiv after 30 mins by CD spectra analysis | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 2. | ALA4043740 | B | Binding affinity to human telomeric 26 G-quadruplex DNA assessed as change in melting temperature at 10 molequiv after 30 mins by CD spectra analysis | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 3. | ALA4043741 | B | Binding affinity to human telomeric 23-p G-quadruplex DNA assessed as change in melting temperature at 10 molequiv after 30 mins by CD spectra analysis | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 4. | ALA4043742 | B | Binding affinity to human telomeric 23-p G-quadruplex DNA assessed as increase in melting temperature up to 240 uM after 30 mins by CD spectra analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 5. | ALA4043746 | B | Binding affinity to 12-mer duplex DNA (unknown origin) at 10 molequiv after 30 mins by CD spectra analysis | Not specified | 3 | assay format | Scientific Literature | ||
| 6. | ALA4043750 | B | Binding affinity to G-quadruplex DNA in human BJeH-LT cells at 1 uM after 24 hrs by hoechst staining-based immunofluorescence analysis | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 7. | ALA4043751 | F | Induction of DNA damage in human BJeH-LT cells assessed as increase in gamma-H2AX foci formation at 1 uM after 24 hrs by hoechst staining-based immunofluorescence analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 8. | ALA4043752 | A | Induction of DNA damage in human hTERT-BJ cells assessed as increase in gamma-H2AX foci formation at 1 uM after 24 hrs by hoechst staining-based immunofluorescence analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 9. | ALA4043753 | F | Induction of DNA damage in human BJeH-LT cells assessed as increase in telomere's dysfunction induced foci positive nuclei at 1 uM after 24 hrs by hoechst staining-based immunofluorescence analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 10. | ALA4043760 | F | Induction of DNA damage in human BJeH-LT cells assessed as increase in gamma-H2AX foci formation at 1 uM after 24 hrs followed by compound washout by hoechst staining-based immunofluorescence analysis | Homo sapiens | 8 | cell-based format | Scientific Literature |
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