| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3992284 | B | Binding affinity to recombinant full-length N-terminal hexahistidine-tagged c-Myc (353 to 437 residues) bHLH-ZIP domain (unknown origin) expressed in Escherichia coli BL21 DE3 (pLysS) by fluorescence polarization assay | Homo sapiens | 27 | assay format | Patent Bioactivity Data | ||
| 2. | ALA3992286 | B | Binding affinity to human hexahistidine-tagged Max p21 bHLH-ZIP domain expressed in Escherichia coli M15 (pRep4) at 10 uM by fluorescence polarization assay | Homo sapiens | 6 | assay format | Patent Bioactivity Data | ||
| 3. | ALA3992289 | B | Binding affinity to recombinant full-length N-terminal hexahistidine-tagged c-Myc (353 to 437 residues) bHLH-ZIP domain (unknown origin) expressed in Escherichia coli BL21 DE3 (pLysS) assessed as changes in shape or intensity of CD spectrum at 5 uM by circular dichroism assay | Homo sapiens | 6 | assay format | Patent Bioactivity Data | ||
| 4. | ALA3992294 | B | Inhibition of recombinant full-length N-terminal hexahistidine-tagged c-Myc (353 to 437 residues) bHLH-ZIP domain (unknown origin) expressed in Escherichia coli BL21 DE3 (pLysS)/human hexahistidine-tagged Max p21 expressed in Escherichia coli M15 (pRep4) assessed as disruption of E-Box DNA binding preincubated for 30 mins with c-Myc followed by Max p21 and E-box element addition measured after 15 mins by electrophoretic mobility shift assay | Homo sapiens | 6 | assay format | Patent Bioactivity Data | ||
| 5. | ALA3992296 | F | Cytotoxicity against human HL60 cells expressing c-Myc assessed as growth inhibition after 4 to 5 days by MTT assay | Homo sapiens | 16 | cell-based format | Patent Bioactivity Data | ||
| 6. | ALA3992297 | F | Cytotoxicity against human Daudi Burkitt lymphoma cells expressing c-Myc assessed as growth inhibition after 4 to 5 days by MTT assay | Homo sapiens | 15 | cell-based format | Patent Bioactivity Data | ||
| 7. | ALA3992298 | A | Cytotoxicity against non-transformed rat TGR1 assessed as growth inhibition after 4 to 5 days by MTT assay | Rattus norvegicus | 11 | cell-based format | Patent Bioactivity Data | ||
| 8. | ALA3992299 | A | Cytotoxicity against c-Myc null rat TGR1 reconstituted with HMGA1b or MT-MC1 assessed as growth inhibition after 4 to 5 days by MTT assay | Rattus norvegicus | 11 | cell-based format | Patent Bioactivity Data |
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