# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4047162 | Functional | Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assay | Homo sapiens | 20 | ALA4043225 | cell-based format | Scientific Literature | |
2. | ALA4047164 | ADME | Apparent permeability of the compound in MDCK cells expressing human MRDR1 at 3 uM after 60 mins in presence of P-gp inhibitor GF120918A by LC-MS/MS analysis | Canis lupus familiaris | 19 | ALA4043225 | cell-based format | Scientific Literature | |
3. | ALA4047165 | ADME | Half-life in Sprague-Dawley rat cecal homogenates at 10 uM by LC-MS/MS analysis | Rattus norvegicus | 19 | ALA4043225 | tissue-based format | Scientific Literature |