| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4012197 | A | Total plasma concentration in C57Bl/6 mouse at 30 mg/kg, po | Mus musculus | 1 | ALA4011598 | organism-based format | Scientific Literature | |
| 2. | ALA4012198 | F | Antipruriceptive activity in C57Bl/6 mouse assessed as reduction in number of histamine-induced scratching bouts at 30 to 300 mg/kg, po administered 4 hrs prior to histamine challenge measured over 15 mins | Mus musculus | 1 | ALA4011598 | organism-based format | Scientific Literature | |
| 3. | ALA4012199 | A | Unbound clearance in rat at 0.5 mg/kg, iv | Rattus norvegicus | 8 | ALA4011598 | organism-based format | Scientific Literature | |
| 4. | ALA4012200 | B | Inhibition of human Nav1.7 expressed in HEK293 cells assessed as reduction in peak inward current by ionworks quattro electrophysiology assay | Homo sapiens | 1 | ALA4011598 | cell-based format | Scientific Literature | |
| 5. | ALA4012201 | B | Inhibition of human Nav1.5 expressed in HEK293 cells assessed as reduction in peak inward current by ionworks quattro electrophysiology assay | Homo sapiens | 23 | ALA4011598 | cell-based format | Scientific Literature | |
| 6. | ALA4012202 | B | Inhibition of human Nav1.1 expressed in HEK293 cells assessed as reduction in peak inward current by ionworks quattro electrophysiology assay | Homo sapiens | 1 | ALA4011598 | cell-based format | Scientific Literature | |
| 7. | ALA4012203 | B | Inhibition of human Nav1.3 expressed in CHO cells assessed as reduction in peak inward current by ionworks quattro electrophysiology assay | Homo sapiens | 1 | ALA4011598 | cell-based format | Scientific Literature | |
| 8. | ALA4012204 | B | Inhibition of human Nav1.4 expressed in HEK293 cells assessed as reduction in peak inward current by ionworks quattro electrophysiology assay | Homo sapiens | 1 | ALA4011598 | cell-based format | Scientific Literature | |
| 9. | ALA4012205 | B | Inhibition of human Nav1.6 expressed in HEK293 cells assessed as reduction in peak inward current by ionworks quattro electrophysiology assay | Homo sapiens | 1 | ALA4011598 | cell-based format | Scientific Literature | |
| 10. | ALA4012206 | A | Unbound clearance in dog at 0.25 mg/kg, iv | Canis lupus familiaris | 10 | ALA4011598 | organism-based format | Scientific Literature | |
| 11. | ALA4012207 | A | Intrinsic clearance in human liver microsomes at 1 uM after 1 to 40 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 21 | ALA4011598 | assay format | Scientific Literature | |
| 12. | ALA4012208 | A | Intrinsic clearance in rat liver microsomes at 1 uM after 1 to 40 mins in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 21 | ALA4011598 | assay format | Scientific Literature | |
| 13. | ALA4012209 | A | Activation of human PXR at 10 uM in presence of rifampicin | Homo sapiens | 24 | ALA4011598 | single protein format | Scientific Literature | |
| 14. | ALA4012210 | A | Total clearance in rat at 0.5 mg/kg, iv | Rattus norvegicus | 8 | ALA4011598 | organism-based format | Scientific Literature | |
| 15. | ALA4012211 | A | Total clearance in dog at 0.25 mg/kg, iv | Canis lupus familiaris | 10 | ALA4011598 | organism-based format | Scientific Literature | |
| 16. | ALA4012212 | A | Volume of distribution at steady state in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | ALA4011598 | organism-based format | Scientific Literature | |
| 17. | ALA4012213 | A | Volume of distribution at steady state in dog at 0.25 mg/kg, iv | Canis lupus familiaris | 1 | ALA4011598 | organism-based format | Scientific Literature | |
| 18. | ALA4012214 | A | Half life in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | ALA4011598 | organism-based format | Scientific Literature | |
| 19. | ALA4012215 | A | Half life in dog at 0.25 mg/kg, iv | Canis lupus familiaris | 1 | ALA4011598 | organism-based format | Scientific Literature | |
| 20. | ALA4012216 | A | AUC in rat at 10 mg/kg, po | Rattus norvegicus | 1 | ALA4011598 | organism-based format | Scientific Literature |
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