# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3998487 | B | Antagonist activity at recombinant human glycine receptor alpha 1 expressed in human tsA201 cells assessed as inhibition of glycine-induced receptor activation after 30 mins by FLIPR membrane potential blue assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
2. | ALA3998488 | B | Antagonist activity at recombinant human glycine receptor alpha 1 beta expressed in human tsA201 cells assessed as inhibition of glycine-induced receptor activation after 30 mins by FLIPR membrane potential blue assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
3. | ALA3998489 | B | Antagonist activity at recombinant human glycine receptor alpha 1 expressed in HEK293 cells assessed as inhibition of glycine-induced current at -50 mV holding potential by whole cell patch-clamp method | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
4. | ALA3998490 | B | Antagonist activity at recombinant human glycine receptor alpha 1 beta expressed in HEK293 cells assessed as inhibition of glycine-induced current at -50mV holding potential by whole cell patch-clamp method | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
5. | ALA3998491 | B | Displacement of [3H]strychnine from glycine receptor alpha 1 in rat brain synaptic membranes | Rattus norvegicus | 2 | cell membrane format | Scientific Literature | ||
6. | ALA3998493 | B | Selectivity ratio of IC50 for recombinant human glycine receptor alpha 1 beta expressed in human tsA201 cells to IC50 for recombinant human glycine receptor alpha 1 expressed in human tsA201 cells | Homo sapiens | 4 | cell-based format | Scientific Literature |