# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4037493 | F | Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulation after 30 mins by scintillation and luminescence counting method | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
2. | ALA4037495 | F | Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulation after 30 mins by scintillation and luminescence counting method | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
3. | ALA4037496 | F | Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulation after 30 mins by scintillation and luminescence counting method | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
4. | ALA4037497 | F | Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulation after 30 mins by scintillation and luminescence counting method | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
5. | ALA4037498 | F | Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
6. | ALA4037499 | F | Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
7. | ALA4037502 | B | Selectivity ratio of EC50 for mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulation to EC50 for mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulation | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
8. | ALA4037503 | B | Selectivity ratio of EC50 for mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation to EC50 for mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation | Homo sapiens | 48 | cell-based format | Scientific Literature | ||
9. | ALA4037511 | B | Agonist activity at mGlu4 in Wistar rat striatum assessed as decrease in corticostriatal glutamatergic excitatory post-synaptic potential by whole cell patch clamp assay | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
10. | ALA4037519 | B | Agonist activity at mGlu4 in Wistar rat striatum assessed as decrease in striatal GABAergic inhibitory post-synaptic potential by whole cell patch clamp assay | Rattus norvegicus | 1 | assay format | Scientific Literature |