| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4008461 | B | Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT-3 enzyme coupled assay | Mus musculus | 39 | assay format | Scientific Literature | ||
| 2. | ALA4008462 | F | Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability after 56 hrs by MTT assay | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 3. | ALA4008463 | B | Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levels | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4008470 | A | Drug metabolism in human liver microsomes assessed as aliphatic hydroxylation of paraffin linkers by LC-ESI-MS or LC-UV analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA4008471 | A | Stability in human liver microsomes after 60 mins by LC-ESI-MS analysis | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 6. | ALA4008472 | A | Stability in Wistar Han rat liver microsomes after 60 mins by LC-ESI-MS analysis | Rattus norvegicus | 4 | assay format | Scientific Literature | ||
| 7. | ALA4008473 | A | Drug metabolism in Wistar Han rat liver microsomes assessed as mixed function oxidase mediated compound cleavage by measuring compound remaining after 60 mins in presence of NADPH-regenerating system by LC-UV analysis | Rattus norvegicus | 5 | assay format | Scientific Literature | ||
| 8. | ALA4008474 | A | Drug metabolism in human liver microsomes assessed as mixed function oxidase mediated compound cleavage by measuring compound remaining after 60 mins in presence of NADPH-regenerating system by LC-UV analysis | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 9. | ALA4008475 | A | Stability in Wistar Han rat liver microsomes assessed as mixed function oxidase mediated compound cleavage after 60 mins in presence of NADPH-regenerating system by LC-UV analysis | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
| 10. | ALA4008476 | A | Stability in human liver microsomes assessed as mixed function oxidase mediated compound cleavage after 60 mins in presence of NADPH-regenerating system by LC-UV analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 11. | ALA4008487 | A | Drug metabolism in human liver microsomes assessed as aromatic hydroxylation of biphenyl moiety by LC-ESI-MS or LC-UV analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA4008488 | A | Drug metabolism in human liver microsomes assessed as oxidative N-dealkylation by LC-ESI-MS or LC-UV analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4008489 | A | Drug metabolism in Wistar Han rat liver microsomes assessed as aliphatic hydroxylation of paraffin linkers by LC-ESI-MS or LC-UV analysis | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 14. | ALA4008490 | A | Drug metabolism in Wistar Han rat liver microsomes assessed as aromatic hydroxylation of biphenyl moiety by LC-ESI-MS or LC-UV analysis | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 15. | ALA4008491 | A | Drug metabolism in Wistar Han rat liver microsomes assessed as oxidative N-dealkylation by LC-ESI-MS or LC-UV analysis | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 16. | ALA4362366 | P | Thermodynamic solubility of compound in water after 24 hrs by LC-UV based shake flask method | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 17. | ALA4362367 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining at 50 uM in absence of NADPH for 60 mins by LC-ESI/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 18. | ALA4362368 | A | Metabolic stability in Wistar Han rat liver microsomes assessed as parent compound remaining at 50 uM in absence of NADPH for 60 mins by LC-ESI/MS analysis | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
| 19. | ALA4362372 | T | Genotoxicity in human primary lymphocytes in presence of S9 fraction by GreenScreen assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4362383 | A | Glutathione reactivity in Wistar Han rat liver microsomes assessed as GSH-compound adduct formation measured after 60 mins in absence of NADPH by LC-ESI/MS analysis | Rattus norvegicus | 1 | microsome format | Scientific Literature |
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