# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4010329 | A | Drug uptake in HEK293 cells at 10 nM in presence of vacuolar type ATPase inhibitor bafilomycin measured after 2.5 hrs | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA4010330 | A | Drug uptake in HEK293 cells at 10 nM in presence of vacuolar type ATPase inhibitor concanamycin A measured after 2.5 hrs | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
3. | ALA4010333 | A | Drug uptake in lymphoblasts (unknown origin) at 10 nM in presence of vacuolar type ATPase inhibitor concanamycin A measured after 2.5 hrs | Not specified | 4 | cell-based format | Scientific Literature | ||
4. | ALA4010334 | A | Drug uptake in lymphoblasts (unknown origin) at 10 nM in presence of vacuolar type ATPase inhibitor bafilomycin measured after 2.5 hrs | Not specified | 4 | cell-based format | Scientific Literature | ||
5. | ALA4010335 | B | Inhibition of human DcpS assessed as increase in SMN2 promoter activity | Homo sapiens | 29 | single protein format | Scientific Literature | ||
6. | ALA4010336 | A | Inhibition of DHFR (unknown origin) | Homo sapiens | 17 | single protein format | Scientific Literature | ||
7. | ALA4010337 | A | Apparent intrinsic clearance in human liver microsomes at 1 uM | Homo sapiens | 3 | assay format | Scientific Literature | ||
8. | ALA4010338 | A | Apparent passive permeability across apical to basolateral side in RRCK2 cells at 2 uM | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
9. | ALA4010339 | A | Efflux ratio of permeability from basolateral to apical over apical to basolateral side of MDCK cells expressing MDR1 | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
10. | ALA4010340 | P | Kinetic solubility of the compound at pH 6.5 | 3 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA4010341 | P | Lipophilicity, log D of the compound at pH 7.4 | 3 | small-molecule physicochemical format | Scientific Literature | |||
12. | ALA4010346 | A | Stability in human liver microsomes at 1 uM | Homo sapiens | 3 | assay format | Scientific Literature |