# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4009334 | B | Inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as reduction in dehydrogenase activity by measuring NAD(P)H level preincubated for 2 mins followed by addition of propionaldehyde as substrate in presence of NAD+ by spectrophotometric method | Homo sapiens | 15 | ALA4007427 | assay format | Scientific Literature | |
2. | ALA4009335 | B | Inhibition of full length recombinant human ALDH1B1 expressed in Escherichia coli TunerDE3 assessed as reduction in dehydrogenase activity by measuring NAD(P)H level preincubated for 2 mins followed by addition of propionaldehyde as substrate in presence of NAD+ by spectrophotometric method | Homo sapiens | 12 | ALA4007427 | assay format | Scientific Literature | |
3. | ALA4009337 | B | Inhibition of full length recombinant human ALDH1A1 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase activity by measuring NAD(P)H level preincubated for 2 mins followed by addition of propionaldehyde as substrate in presence of NAD+ by spectrophotometric method | Homo sapiens | 15 | ALA4007427 | assay format | Scientific Literature | |
4. | ALA4009339 | B | Inhibition of full length recombinant human ALDH1A2 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase activity by measuring NAD(P)H level preincubated for 2 mins followed by addition of propionaldehyde as substrate in presence of NAD+ by spectrophotometric method | Homo sapiens | 12 | ALA4007427 | assay format | Scientific Literature | |
5. | ALA4009341 | B | Inhibition of full length recombinant human ALDH1A3 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase activity by measuring NAD(P)H level preincubated for 2 mins followed by addition of propionaldehyde as substrate in presence of NAD+ by spectrophotometric method | Homo sapiens | 10 | ALA4007427 | assay format | Scientific Literature | |
6. | ALA4009342 | B | Inhibition of rat ALDH1L1 assessed as reduction in dehydrogenase activity by measuring NAD(P)H level preincubated for 2 mins followed by addition of propionaldehyde as substrate in presence of NAD+ by spectrophotometric method | Rattus norvegicus | 5 | ALA4007427 | single protein format | Scientific Literature | |
7. | ALA4009343 | B | Inhibition of full length recombinant human ALDH3A1 expressed in Escherichia coli BL21(DE3) assessed as reduction in dehydrogenase activity by measuring NAD(P)H level preincubated for 2 mins followed by addition of benzaldehyde as substrate in presence of NADP+ by spectrophotometric method | Homo sapiens | 15 | ALA4007427 | assay format | Scientific Literature | |
8. | ALA4009344 | B | Inhibition of full length recombinant human ALDH1A1 expressed in Escherichia coli BL21(DE3) assessed as remaining dehydrogenase activity by measuring NAD(P)H level at 10 uM preincubated for 2 mins followed by addition of propionaldehyde as substrate in presence of NAD+ by spectrophotometric method | Homo sapiens | 37 | ALA4007427 | assay format | Scientific Literature | |
9. | ALA4009345 | B | Inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as remaining dehydrogenase activity by measuring NAD(P)H level at 10 uM preincubated for 2 mins followed by addition of propionaldehyde as substrate in presence of NAD+ by spectrophotometric method | Homo sapiens | 37 | ALA4007427 | assay format | Scientific Literature | |
10. | ALA4009346 | B | Inhibition of full length recombinant human ALDH3A1 expressed in Escherichia coli BL21(DE3) assessed as remaining dehydrogenase activity by measuring NAD(P)H level at 10 uM preincubated for 2 mins followed by addition of propionaldehyde as substrate in presence of NAD+ by spectrophotometric method | Homo sapiens | 37 | ALA4007427 | assay format | Scientific Literature | |
11. | ALA4009349 | P | Lipophilicity, log P of the compound | 37 | ALA4007427 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA4009354 | B | Competitive inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as reduction in dehydrogenase activity using propionaldehyde as substrate in presence of varying levels NAD+ by Lineweaver-Burk plot analysis | Homo sapiens | 5 | ALA4007427 | assay format | Scientific Literature | |
13. | ALA5150275 | B | Inhibition of human ALDH2 | Homo sapiens | 5 | ALA5149964 | single protein format | Scientific Literature |