# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4051994 | B | Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at 100 uM at pH 5.5 after 2 mins at -20 mV holding potential by two-electrode voltage clamp assay relative to control | Influenza A virus (A/udorn/1972(H3N2)) | 12 | cell-based format | Scientific Literature | ||
2. | ALA4051995 | B | Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 after 2 mins at -20 mV holding potential by two-electrode voltage clamp assay | Influenza A virus (A/udorn/1972(H3N2)) | 12 | cell-based format | Scientific Literature | ||
3. | ALA4052000 | B | Inhibition of Influenza A virus A/Udorn/72 amantadine-resistant M2 proton channel V27A mutant expressed in Xenopus laevis oocytes at 100 uM at pH 5.5 after 2 mins at -20 mV holding potential by two-electrode voltage clamp assay relative to control | Influenza A virus (A/udorn/1972(H3N2)) | 12 | cell-based format | Scientific Literature | ||
4. | ALA4052001 | B | Inhibition of Influenza A virus A/Udorn/72 amantadine-resistant M2 proton channel V27A mutant expressed in Xenopus laevis oocytes at pH 5.5 after 2 mins at -20 mV holding potential by two-electrode voltage clamp assay relative to control | Influenza A virus (A/udorn/1972(H3N2)) | 12 | cell-based format | Scientific Literature | ||
5. | ALA4052002 | B | Inhibition of Influenza A virus A/Udorn/72 amantadine-resistant M2 proton channel S31N mutant expressed in Xenopus laevis oocytes at 100 uM at pH 5.5 after 2 mins at -20 mV holding potential by two-electrode voltage clamp assay relative to control | Influenza A virus (A/udorn/1972(H3N2)) | 12 | cell-based format | Scientific Literature | ||
6. | ALA4052004 | F | Antiviral activity against Influenza A virus A//HK/7/87 (H3N2) expressing wild-type M2 proton channel infected in MDCK cells assessed as reduction in plaque formation preincubated with virus for 1 hr followed by addition to cells measured after 72 hrs by crystal violet staining based assay | Influenza A virus (A/Hong Kong/7/1987(H3N2)) | 14 | cell-based format | Scientific Literature | ||
7. | ALA4052005 | F | Antiviral activity against Influenza A virus A//HK/7/87 (H3N2) expressing wild-type M2 proton channel infected in MDCK cells assessed as reduction in viral yield after 24 hrs by RT-qPCR method | Influenza A virus (A/Hong Kong/7/1987(H3N2)) | 14 | cell-based format | Scientific Literature | ||
8. | ALA4052006 | A | Cytotoxicity against MDCK cells assessed as reduction in cell viability after 72 hrs by MTS assay | Canis lupus familiaris | 14 | cell-based format | Scientific Literature | ||
9. | ALA4052007 | F | Antiviral activity against Influenza A virus A/PR/8/34 expressing amantadine-resistant M2 proton channel S31N mutant infected in MDCK cells | Influenza A virus | 12 | cell-based format | Scientific Literature | ||
10. | ALA4052009 | F | Antiviral activity against Influenza A virus A/WSN/33 (H1N1) expressing M2 proton channel N31S/V27A double mutant infected in MDCK cells assessed as reduction in plaque formation measured at 46 hrs by crystal violet staining based assay | Influenza A virus (A/WSN/1933(H1N1)) | 5 | cell-based format | Scientific Literature |