# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4014782 | Functional | Antidiabetic activity in HFD-fed C57BL/6 mouse assessed as decrease in blood glucose level at 10 to 30 mg/kg, ip | Mus musculus | 1 | ALA4014286 | organism-based format | Scientific Literature | |
2. | ALA4014788 | Functional | Antidiabetic activity in HFD-fed C57BL/6 mouse assessed as decrease in plasma insulin level at 30 mg/kg, ip | Mus musculus | 1 | ALA4014286 | organism-based format | Scientific Literature | |
3. | ALA4014790 | ADME | Oral bioavailability in mouse | Mus musculus | 1 | ALA4014286 | organism-based format | Scientific Literature | |
4. | ALA4014791 | Binding | Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH coupled spectrophotometric assay | Homo sapiens | 7 | ALA4014286 | single protein format | Scientific Literature | |
5. | ALA4014792 | Binding | Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH coupled spectrophotometric assay relative to control | Homo sapiens | 7 | ALA4014286 | single protein format | Scientific Literature | |
6. | ALA4014793 | ADME | Clearance in rat | Rattus norvegicus | 7 | ALA4014286 | assay format | Scientific Literature | |
7. | ALA4014794 | ADME | Mean residence time in rat | Rattus norvegicus | 7 | ALA4014286 | assay format | Scientific Literature | |
8. | ALA4014795 | ADME | Half life in rat | Rattus norvegicus | 7 | ALA4014286 | assay format | Scientific Literature | |
9. | ALA4014796 | ADME | Oral bioavailability in rat | Rattus norvegicus | 7 | ALA4014286 | organism-based format | Scientific Literature | |
10. | ALA4014797 | Physicochemical | Apparent permeability of the compound | 7 | ALA4014286 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4014800 | ADME | Total drug level in HFD-fed C57BL/6 mouse liver at 30 mg/kg, ip measured 4 hrs post dose | Mus musculus | 1 | ALA4014286 | organism-based format | Scientific Literature | |
12. | ALA4014801 | ADME | Total drug level in HFD-fed C57BL/6 mouse pancreas at 30 mg/kg, ip measured 4 hrs post dose | Mus musculus | 1 | ALA4014286 | organism-based format | Scientific Literature | |
13. | ALA4014802 | ADME | Total drug level in HFD-fed C57BL/6 mouse plasma at 30 mg/kg, ip measured 4 hrs post dose | Mus musculus | 1 | ALA4014286 | organism-based format | Scientific Literature | |
14. | ALA4014803 | ADME | Ratio of drug level in HFD-fed C57BL/6 mouse liver to plasma at 30 mg/kg, ip measured 4 hrs post dose | Mus musculus | 1 | ALA4014286 | organism-based format | Scientific Literature | |
15. | ALA4014804 | ADME | Ratio of drug level in HFD-fed C57BL/6 mouse pancreas to plasma at 30 mg/kg, ip measured 4 hrs post dose | Mus musculus | 1 | ALA4014286 | organism-based format | Scientific Literature | |
16. | ALA4014805 | ADME | Ratio of drug level in HFD-fed C57BL/6 mouse liver to pancreas at 30 mg/kg, ip measured 4 hrs post dose | Mus musculus | 1 | ALA4014286 | organism-based format | Scientific Literature | |
17. | ALA4014821 | Toxicity | Toxicity in HFD-fed C57BL/6 mouse assessed as increase in plasma insulin level at 10 mg/kg, ip | Mus musculus | 1 | ALA4014286 | organism-based format | Scientific Literature |