#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4032660	B	Agonist activity at recombinant human GST-tagged FXR ligand binding domain (193 to 472 residues) expressed in baculovirus infected insect cells assessed as induction of interaction with biotin labelled SRC-1 after 1 hr by HTRF assay	Homo sapiens	15	ALA4028903	cell-based format	Scientific Literature
2.	ALA4032661	B	Agonist activity at recombinant human GST-tagged FXR ligand binding domain (193 to 472 residues) expressed in baculovirus infected insect cells assessed as induction of interaction with biotin labelled SRC-1 after 1 hr by HTRF assay relative to GW4064	Homo sapiens	14	ALA4028903	cell-based format	Scientific Literature
3.	ALA4032662	B	Agonist activity at human FXR expressed in HEK293T cells assessed as BSEP promoter driven cellular transcriptional activity after 24 hrs by luciferase reporter gene assay	Homo sapiens	15	ALA4028903	cell-based format	Scientific Literature
4.	ALA4032663	B	Agonist activity at human FXR expressed in HEK293T cells assessed as BSEP promoter driven cellular transcriptional activity after 24 hrs by luciferase reporter gene assay relative to GW4064	Homo sapiens	14	ALA4028903	cell-based format	Scientific Literature
5.	ALA4032664	P	Solubility of the compound in fasted state simulated intestinal fluid at pH 6.8		11	ALA4028903	small-molecule physicochemical format	Scientific Literature
6.	ALA4032666	A	Extraction ratio in rat liver microsomes	Rattus norvegicus	11	ALA4028903	assay format	Scientific Literature
7.	ALA4032667	A	Extraction ratio in human liver microsomes	Homo sapiens	11	ALA4028903	assay format	Scientific Literature
8.	ALA4032668	A	Clearance in rat at 3 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	8	ALA4028903	organism-based format	Scientific Literature
9.	ALA4032669	A	Volume of distribution at steady state in rat at 3 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	8	ALA4028903	organism-based format	Scientific Literature
10.	ALA4032670	A	Terminal half life in rat at 3 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	8	ALA4028903	organism-based format	Scientific Literature
11.	ALA4032671	A	AUC in rat at 10 mg/kg, po administered via gavage by LC-MS/MS analysis	Rattus norvegicus	8	ALA4028903	organism-based format	Scientific Literature
12.	ALA4032672	A	Cmax in rat at 10 mg/kg, po administered via gavage by LC-MS/MS analysis	Rattus norvegicus	8	ALA4028903	organism-based format	Scientific Literature
13.	ALA4032673	A	Oral bioavailability in rat at 10 mg/kg administered via gavage by LC-MS/MS analysis	Rattus norvegicus	8	ALA4028903	organism-based format	Scientific Literature
14.	ALA5247740	B	Agonist activity at human GST-tagged FXR LBD (193 to 472 residues) by FRET assay	Homo sapiens	4	ALA5247574	single protein format	Scientific Literature