| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4037495 | F | Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulation after 30 mins by scintillation and luminescence counting method | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 2. | ALA4037496 | F | Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulation after 30 mins by scintillation and luminescence counting method | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 3. | ALA4037498 | F | Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
| 4. | ALA4037499 | F | Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
| 5. | ALA4037500 | F | Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
| 6. | ALA4037501 | F | Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 7. | ALA4037503 | B | Selectivity ratio of EC50 for mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation to EC50 for mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation | Homo sapiens | 48 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!