#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4055636	Binding	Inhibition of human VAP-1 expressed in CHO cells using 14C-benzylamine as substrate preincubated for 20 mins followed by substrate addition measured after 1 hr by scintillation spectrometric analysis	Homo sapiens	14	ALA4052665	cell-based format	Scientific Literature
2.	ALA4055637	Binding	Inhibition of rat VAP-1 expressed in CHO cells using 14C-benzylamine as substrate preincubated for 20 mins followed by substrate addition measured after 1 hr by scintillation spectrometric analysis	Rattus norvegicus	7	ALA4052665	cell-based format	Scientific Literature
3.	ALA4055638	ADME	Inhibition of CYP3A4 in human liver microsomes assessed as residual activity at 5 uM using midazolam as substrate after 20 mins by LC-MS/MS analysis	Homo sapiens	11	ALA4052665	assay format	Scientific Literature
4.	ALA4055639	ADME	Inhibition of CYP2C19 in human liver microsomes assessed as residual activity at 5 uM using S-mephenytoin as substrate after 20 mins by LC-MS/MS analysis	Homo sapiens	11	ALA4052665	assay format	Scientific Literature
5.	ALA4055640	Functional	Inhibition of VAP-1 in Wistar rat plasma at 1 mg/kg, po using 14C-benzylamine as substrate preincubated for 20 mins followed by substrate addition measured after 1 hr by scintillation spectrometric analysis	Rattus norvegicus	3	ALA4052665	organism-based format	Scientific Literature
6.	ALA4055641	Functional	Inhibition of VAP-1 in Wistar rat plasma at 1 mg/kg, po using 14C-benzylamine as substrate preincubated for 20 mins followed by substrate addition measured after 6 hr by scintillation spectrometric analysis	Rattus norvegicus	2	ALA4052665	organism-based format	Scientific Literature
7.	ALA4055642	Functional	Inhibition of VAP-1 in Wistar rat plasma at 0.3 mg/kg, po using 14C-benzylamine as substrate preincubated for 20 mins followed by substrate addition measured after 1 hr by scintillation spectrometric analysis	Rattus norvegicus	1	ALA4052665	organism-based format	Scientific Literature
8.	ALA4055643	Functional	Inhibition of VAP-1 in Wistar rat plasma at 0.3 mg/kg, po using 14C-benzylamine as substrate preincubated for 20 mins followed by substrate addition measured after 6 hr by scintillation spectrometric analysis	Rattus norvegicus	1	ALA4052665	organism-based format	Scientific Literature
9.	ALA4055644	Physicochemical	Aqueous solubility of the compound in solution at pH 6.8		2	ALA4052665	small-molecule physicochemical format	Scientific Literature
10.	ALA4055645	Physicochemical	Aqueous solubility of the compound in solution at pH 6.8 in presence of 15 mM sodium taurocholate		2	ALA4052665	small-molecule physicochemical format	Scientific Literature
11.	ALA4055646	ADME	AUC (0 to 24 hrs) in Wistar rat at 1 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	1	ALA4052665	organism-based format	Scientific Literature
12.	ALA4055647	ADME	AUC (0 to 24 hrs) in Wistar rat at 1 mg/kg, po by LC-MS/MS analysis	Rattus norvegicus	1	ALA4052665	organism-based format	Scientific Literature
13.	ALA4055648	ADME	Cmax in Wistar rat at 1 mg/kg, po by LC-MS/MS analysis	Rattus norvegicus	1	ALA4052665	organism-based format	Scientific Literature
14.	ALA4055649	ADME	Total clearance in Wistar rat at 1 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	1	ALA4052665	organism-based format	Scientific Literature
15.	ALA4055650	ADME	Half life in Wistar rat at 1 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	1	ALA4052665	organism-based format	Scientific Literature
16.	ALA4055651	ADME	Half life in Wistar rat at 1 mg/kg, po by LC-MS/MS analysis	Rattus norvegicus	1	ALA4052665	organism-based format	Scientific Literature
17.	ALA4055652	ADME	Volume of distribution at steady state in Wistar rat at 1 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	1	ALA4052665	organism-based format	Scientific Literature
18.	ALA4055653	ADME	Oral bioavailability in Wistar rat at 1 mg/kg by LC-MS/MS analysis	Rattus norvegicus	1	ALA4052665	organism-based format	Scientific Literature
19.	ALA4055654	Functional	In vivo inhibition of VAP-1 in STZ-induced diabetic Sprague-Dawley rat assessed as reduction in proteinuria progression at 0.3 to 1 mg/kg, po for 4 weeks measured after 24 hrs by Bradford colorimetric assay	Rattus norvegicus	1	ALA4052665	organism-based format	Scientific Literature
20.	ALA4055655	Functional	In vivo inhibition of VAP-1 in STZ-induced diabetic Sprague-Dawley rat plasma at 0.3 to 1 mg/kg, po for 4 weeks measured after 24 hrs after final dose using 14C-benzylamine as substrate by scintillation spectrometric analysis	Rattus norvegicus	1	ALA4052665	organism-based format	Scientific Literature