# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4019814 | Functional | Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-induced calcium flux preincubated for 10 mins followed by glutamate addition measured for 3 mins by Fluo4-AM dye based fluorescence assay | Homo sapiens | 61 | ALA4017520 | cell-based format | Scientific Literature | |
2. | ALA4019878 | ADME | Drug uptake in Sprague-Dawley rat brain at 10 mg/kg, po after 30 mins post dose administered as single dose by LC-MS/MS analysis | Rattus norvegicus | 18 | ALA4017520 | organism-based format | Scientific Literature | |
3. | ALA4019916 | ADME | Drug uptake in Sprague-Dawley rat brain at 10 mg/kg, po after 90 mins post dose administered as single dose by LC-MS/MS analysis | Rattus norvegicus | 18 | ALA4017520 | organism-based format | Scientific Literature | |
4. | ALA4019917 | ADME | Drug uptake in Sprague-Dawley rat brain at 10 mg/kg, po after 60 mins post dose administered as single dose by LC-MS/MS analysis | Rattus norvegicus | 18 | ALA4017520 | organism-based format | Scientific Literature |