# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4025650 | B | Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mins followed by substrate and cofactor addition after 60 mins by LC/Ms analysis | Rattus norvegicus | 28 | assay format | Scientific Literature | ||
2. | ALA4025651 | B | Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mins followed by substrate and cofactor addition after 60 mins by LC/MS analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
3. | ALA4025654 | A | Inhibition of human hepatic CYP3A4 | Homo sapiens | 7 | single protein format | Scientific Literature | ||
4. | ALA4025655 | A | Inhibition of human hepatic CYP1A2 at 1 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
5. | ALA4025656 | A | Inhibition of human hepatic CYP1A2 at 10 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
6. | ALA4025657 | A | Inhibition of human hepatic CYP2C9 at 1 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
7. | ALA4025658 | A | Inhibition of human hepatic CYP2C9 at 10 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
8. | ALA4025659 | A | Inhibition of human hepatic CYP2C19 at 1 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
9. | ALA4025660 | A | Inhibition of human hepatic CYP2C19 at 10 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
10. | ALA4025661 | A | Inhibition of human hepatic CYP2D6 at 1 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
11. | ALA4025662 | A | Inhibition of human hepatic CYP2D6 at 10 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature |