# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4037806 | A | Half life in human liver microsomes at 10 uM by LC-MS/MS analysis | Homo sapiens | 26 | ALA4033790 | assay format | Scientific Literature | |
2. | ALA4037807 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining at 10 uM after 60 mins by LC-MS analysis | Homo sapiens | 26 | ALA4033790 | assay format | Scientific Literature | |
3. | ALA4037808 | A | Half life in mouse liver microsomes at 10 uM by LC-MS/MS analysis | Mus musculus | 26 | ALA4033790 | assay format | Scientific Literature | |
4. | ALA4037809 | A | Metabolic stability in mouse liver microsomes assessed as parent compound remaining at 10 uM after 60 mins by LC-MS analysis | Mus musculus | 26 | ALA4033790 | assay format | Scientific Literature | |
5. | ALA4037842 | B | Displacement of [3H]-flunitrazepam from rat brain GABA-A receptor benzodiazepine site expressed in HEK293 cell membranes at 10 uM after 60 to 90 mins by scintillation counting | Rattus norvegicus | 10 | ALA4033790 | cell-based format | Scientific Literature | |
6. | ALA4037852 | T | Neurotoxicity in Swiss Webster mouse assessed as induction of motor impairment at 40 mg/kg administered via oral gavage measured after 10 to 60 mins by rotarod method | Mus musculus | 18 | ALA4033790 | organism-based format | Scientific Literature | |
7. | ALA4037904 | B | Positive allosteric modulation of GABA-A receptor alpha6beta3gamma2 (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of EC3 GABA induced currents up to 10 uM at -60 mV holding potential by electrophysiological method | Homo sapiens | 6 | ALA4033790 | cell-based format | Scientific Literature | |
8. | ALA4037910 | B | Displacement of [3H]-dofetilide from human ERG expressed in HEK cell membranes at >10 uM after 60 to 90 mins by scintillation counting | Homo sapiens | 27 | ALA4033790 | cell-based format | Scientific Literature |