# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4059284 | Binding | Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK293 cell membranes after 4 hrs by scintillation counting method | Rattus norvegicus | 41 | ALA4052830 | cell-based format | Scientific Literature | |
2. | ALA4059285 | Binding | Displacement of [3H]epibatidine from rat alpha4beta4 nAChR expressed in HEK293 cell membranes after 4 hrs by scintillation counting method | Rattus norvegicus | 41 | ALA4052830 | cell-based format | Scientific Literature | |
3. | ALA4059286 | Binding | Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK293 cell membranes after 4 hrs by scintillation counting method | Rattus norvegicus | 41 | ALA4052830 | cell-based format | Scientific Literature | |
4. | ALA4059290 | Binding | Antagonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up to 90 secs by FMP assay | Rattus norvegicus | 41 | ALA4052830 | cell-based format | Scientific Literature | |
5. | ALA4059291 | Binding | Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up to 90 secs by FMP assay | Mus musculus | 41 | ALA4052830 | cell-based format | Scientific Literature | |
6. | ALA4059295 | Binding | Agonist activity at human alpha7 nAChR expressed in HEK293 cells co-expressing Ric-3/NACHO assessed as induction of calcium mobilization at 10 uM measured up to 90 secs in presence of PNU-120596 by FLIPR assay | Homo sapiens | 2 | ALA4052830 | cell-based format | Scientific Literature | |
7. | ALA4059302 | Functional | Anti-depressant like activity in sc dosed mouse assessed as increase in swimming activity administered 15 mins prior to testing by forced swim test | Mus musculus | 1 | ALA4052830 | organism-based format | Scientific Literature |