| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3993919 | F | Growth inhibition of human SNU182 cells at <12.5 uM after 48 hrs by CCK8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA3993920 | F | Growth inhibition of human SNU182 cells at <50 uM in presence of zingerone after 48 hrs by CCK8 assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA3993922 | F | Growth inhibition of human SNU182 cells assessed as cell survival at 12.5 uM after 48 hrs by CCK8 assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA3993923 | F | Growth inhibition of human SNU182 cells after 48 hrs by CCK8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3993924 | F | Growth inhibition of human SNU182 cells assessed as cell growth at 50 uM after 48 hrs by CCK8 assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3993925 | F | Inhibition of TGFbeta1-induced epithelial-mesenchymal transition in human SNU182 cells assessed as reduction in downregulation of E-cadherin expression at 12.5 uM preincubated for 2 hrs followed by TGFbeta1 addition measured after 48 hrs by Western blot method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA3993927 | F | Inhibition of TGFbeta1-induced epithelial-mesenchymal transition in human SNU182 cells assessed as reduction in upregulation of Snail expression at 12.5 uM preincubated for 2 hrs followed by TGFbeta1 addition measured after 48 hrs by Western blot method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA3993929 | F | Inhibition of TGFbeta1-induced epithelial-mesenchymal transition in human SNU182 cells assessed as reduction in downregulation of E-cadherin expression preincubated for 2 hrs followed by TGFbeta1 addition measured after 48 hrs in presence of zingerone by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3993931 | F | Inhibition of TGFbeta1-induced epithelial-mesenchymal transition in human SNU182 cells assessed as reduction in upregulation of Snail expression preincubated for 2 hrs followed by TGFbeta1 addition measured after 48 hrs in presence of zingerone by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3993933 | F | Inhibition of TGFbeta1-induced epithelial-mesenchymal transition in human SNU182 cells assessed as reduction in mesenchymal phenotype preincubated for 2 hrs followed by TGFbeta1 addition measured after 48 hrs in presence of zingerone | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3993935 | F | Inhibition of TGFbeta1-induced epithelial-mesenchymal transition in human SNU182 cells assessed as reduction in upregulation of N-cadherin expression preincubated for 2 hrs followed by TGFbeta1 addition measured after 48 hrs in presence of zingerone by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3993937 | B | Inhibition of TGFbeta1-induced SMAD2 phosphorylation in human SNU182 cells at 20 to 40 uM preincubated for 2 hrs followed by TGFbeta1 addition measured after 48 hrs in presence of zingerone by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3993939 | F | Inhibition of TGFbeta1-induced migration in human SNU182 cells at 40 uM measured after 48 hrs in presence of zingerone by wound healing assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3993941 | F | Inhibition of TGFbeta1-induced invasion in human SNU182 cells at 40 uM measured after 48 hrs in presence of zingerone by microscopic method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3993943 | F | Inhibition of TGFbeta1-induced epithelial-mesenchymal transition in human SNU182 cells assessed as reduction in MMP2 mRNA expression at 12.5 uM preincubated for 2 hrs followed by TGFbeta1 addition measured after 48 hrs by qRT-PCR method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA3993945 | F | Inhibition of TGFbeta1-induced epithelial-mesenchymal transition in human SNU182 cells assessed as reduction in MMP9 mRNA expression at 12.5 uM preincubated for 2 hrs followed by TGFbeta1 addition measured after 48 hrs by qRT-PCR method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA3993947 | F | Inhibition of TGFbeta1-induced epithelial-mesenchymal transition in human SNU182 cells assessed as reduction in MMP2 mRNA expression preincubated for 2 hrs followed by TGFbeta1 addition measured after 48 hrs in presence of zingerone by qRT-PCR method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3993949 | F | Inhibition of TGFbeta1-induced epithelial-mesenchymal transition in human SNU182 cells assessed as reduction in MMP9 mRNA expression preincubated for 2 hrs followed by TGFbeta1 addition measured after 48 hrs in presence of zingerone by qRT-PCR method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3993951 | F | Inhibition of TGFbeta1-induced epithelial-mesenchymal transition in human SNU182 cells assessed as reduction in MMP9 activity measured after 48 hrs in presence of zingerone by gelatin zymography assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3993953 | F | Inhibition of TGFbeta1-induced epithelial-mesenchymal transition in human SNU182 cells assessed as reduction in MMP2 activity measured after 48 hrs in presence of zingerone by gelatin zymography assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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