# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4017288 | B | Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells using single stranded poly(U) RNA as substrate after 30 mins by ADP-Glo luminescence assay | Homo sapiens | 12 | ALA4014351 | cell-based format | Scientific Literature | |
2. | ALA4017289 | B | Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) using single stranded poly(U) RNA as substrate after 30 mins by ADP-Glo luminescence assay | Homo sapiens | 5 | ALA4014351 | assay format | Scientific Literature | |
3. | ALA4017290 | B | Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) using single stranded poly(U) RNA as substrate after 30 mins by ADP-Glo luminescence assay | Homo sapiens | 5 | ALA4014351 | assay format | Scientific Literature | |
4. | ALA4017291 | B | Inhibition of full length recombinant human N-terminal FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 insect cells using single stranded poly(U) RNA as substrate after 30 mins by ADP-Glo luminescence assay | Homo sapiens | 5 | ALA4014351 | cell-based format | Scientific Literature | |
5. | ALA4017292 | P | Solubility of the compound in pH 6.8 aqueous buffer by UV absorbance method | 4 | ALA4014351 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4017295 | P | Permeability of the compound at 10 uM at pH 7.4 after 3 hrs by PAMPA | 4 | ALA4014351 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4017296 | P | 1-octanol/aqueous buffer distribution coefficient, log D of the compound at pH 7.4 by chromatographic method | 4 | ALA4014351 | small-molecule physicochemical format | Scientific Literature |