# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4009128 | A | Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated for 24 hrs measured after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
2. | ALA4009129 | U | Selectivity ratio of IC50 for substrate activity at CPR in human L02 cells assessed as cell growth inhibition to IC50 for substrate activity at NQO1 in human A549 cells assessed as cell growth inhibition | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
3. | ALA4009135 | B | Substrate activity at recombinant human NQO1 expressed in Escherichia coli assessed as compound reduction rate by measuring NADPH consumption per umol of enzyme preincubated for 3 mins followed by NADPH addition measured for 5 mins at 2 sec time interval by UV-Visible spectroscopic method | Homo sapiens | 23 | assay format | Scientific Literature | ||
4. | ALA4009136 | A | Substrate activity at recombinant human CPR expressed in baculovirus infected insect cells assessed as compound reduction rate by measuring NADPH consumption per umol of enzyme preincubated for 3 mins followed by NADPH addition measured for 5 mins at 2 sec time interval by UV-Visible spectroscopic method | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
5. | ALA4009137 | U | Selectivity ratio of compound reduction rate catalyzed by recombinant human NQO1 expressed in Escherichia coli to compound reduction rate catalyzed by recombinant human CPR expressed in baculovirus infected insect cells | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
6. | ALA4009139 | B | Substrate activity at NQO1 in human A549 cells assessed as NQO1-mediated two-electron reduction of compound by measuring cell growth inhibition treated for 24 hrs measured after 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature |