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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4014783 Functional Antidiabetic activity in HFD-fed C57BL/6 mouse assessed as decrease in blood glucose level at 10 mg/kg, po Mus musculus 2 ALA4014286 organism-based format Scientific Literature 2. ALA4014784 ADME Ratio of drug level in HFD-fed C57BL/6 mouse liver to plasma at 10 mg/kg, po measured 4 hrs post dose Mus musculus 2 ALA4014286 organism-based format Scientific Literature 3. ALA4014785 ADME Total drug level in HFD-fed C57BL/6 mouse plasma at 10 mg/kg, po measured 4 hrs post dose Mus musculus 2 ALA4014286 organism-based format Scientific Literature 4. ALA4014786 ADME Total drug level in HFD-fed C57BL/6 mouse pancreas at 10 mg/kg, po measured 4 hrs post dose Mus musculus 2 ALA4014286 organism-based format Scientific Literature 5. ALA4014787 ADME Total drug level in HFD-fed C57BL/6 mouse liver at 10 mg/kg, po measured 4 hrs post dose Mus musculus 2 ALA4014286 organism-based format Scientific Literature 6. ALA4014789 Toxicity Toxicity in HFD-fed C57BL/6 mouse assessed as increase in plasma insulin level at 10 mg/kg, po Mus musculus 2 ALA4014286 organism-based format Scientific Literature 7. ALA4014791 Binding Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH coupled spectrophotometric assay Homo sapiens 7 ALA4014286 single protein format Scientific Literature 8. ALA4014792 Binding Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH coupled spectrophotometric assay relative to control Homo sapiens 7 ALA4014286 single protein format Scientific Literature 9. ALA4014793 ADME Clearance in rat Rattus norvegicus 7 ALA4014286 assay format Scientific Literature 10. ALA4014794 ADME Mean residence time in rat Rattus norvegicus 7 ALA4014286 assay format Scientific Literature 11. ALA4014795 ADME Half life in rat Rattus norvegicus 7 ALA4014286 assay format Scientific Literature 12. ALA4014796 ADME Oral bioavailability in rat Rattus norvegicus 7 ALA4014286 organism-based format Scientific Literature 13. ALA4014797 Physicochemical Apparent permeability of the compound 7 ALA4014286 small-molecule physicochemical format Scientific Literature 14. ALA4014798 ADME Ratio of drug level in HFD-fed C57BL/6 mouse pancreas to plasma at 10 mg/kg, po measured 4 hrs post dose Mus musculus 2 ALA4014286 organism-based format Scientific Literature 15. ALA4014799 ADME Ratio of drug level in HFD-fed C57BL/6 mouse liver to pancreas at 10 mg/kg, po measured 4 hrs post dose Mus musculus 2 ALA4014286 organism-based format Scientific Literature 16. ALA4014806 Functional Antidiabetic activity in HFD-fed C57BL/6 mouse assessed as decrease in blood glucose level at 30 mg/kg, po Mus musculus 1 ALA4014286 organism-based format Scientific Literature 17. ALA4014807 ADME Fraction unbound in C57BL/6 mouse plasma Mus musculus 2 ALA4014286 cell-free format Scientific Literature 18. ALA4014808 Toxicity Toxicity in HFD-fed C57BL/6 mouse assessed as increase in plasma insulin level at 30 mg/kg, po Mus musculus 1 ALA4014286 organism-based format Scientific Literature 19. ALA4014809 ADME Total drug level in HFD-fed C57BL/6 mouse liver at 3 mg/kg, po measured 4 hrs post dose Mus musculus 1 ALA4014286 organism-based format Scientific Literature 20. ALA4014810 ADME Total drug level in HFD-fed C57BL/6 mouse pancreas at 3 mg/kg, po measured 4 hrs post dose Mus musculus 1 ALA4014286 organism-based format Scientific Literature