| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4031608 | B | Substrate activity at PTS in CHO cells assessed as reduction in cell viability after 48 hrs in presence of aminoguanidine by MTS assay | Cricetulus griseus | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA4031609 | A | Cytotoxicity against CHO-MG cells assessed as reduction in cell viability after 48 hrs in presence of aminoguanidine by MTS assay | Cricetulus griseus | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA4031610 | U | Selectivity ratio of IC50 for CHO-MG cells to IC50 for PTS in CHO cells | Cricetulus griseus | 10 | cell-based format | Scientific Literature | ||
| 4. | ALA4031642 | B | Increase in SGMS activity in mouse PancO2 cell lysates assessed as induction of NBD-sphingomyelin production at 0.5 uM using C12-NBD-ceramide substrate after 72 hrs by TLC relative to control | Mus musculus | 3 | assay format | Scientific Literature | ||
| 5. | ALA4031643 | B | Increase in SGMS activity in mouse PancO2 cell lysates assessed as induction of NBD-sphingomyelin production at 1 uM using C12-NBD-ceramide substrate after 72 hrs by TLC relative to control | Mus musculus | 3 | assay format | Scientific Literature | ||
| 6. | ALA4377229 | F | Potentiation of doxycycline-induced antibacterial activity against Enterobacter aerogenes EA289 assessed as doxycycline MIC at 2.5 uM after 18 hrs (Rvb = 40 ug/ml) | Klebsiella aerogenes | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA4377230 | F | Potentiation of doxycycline-induced antibacterial activity against Pseudomonas aeruginosa PAO1 assessed as doxycycline MIC at 2.5 uM after 18 hrs (Rvb = 20 ug/ml) | Pseudomonas aeruginosa | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4377231 | F | Potentiation of doxycycline-induced antibacterial activity against Klebsiella pneumoniae KPC2 assessed as doxycycline MIC at 2.5 uM after 18 hrs (Rvb = 10 ug/ml) | Klebsiella pneumoniae | 2 | organism-based format | Scientific Literature |
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