# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3996975 | Functional | Agonist activity at human FFA4 receptor expressed in human U2OS cells co-expressing Galpha16 assessed as calcium mobilization by Fluo-4 dye based FLIPR assay | Homo sapiens | 31 | ALA3994633 | cell-based format | Scientific Literature | |
2. | ALA3996976 | Functional | Agonist activity at human FFA1 receptor expressed in human U2OS cells co-expressing Galpha16 assessed as calcium mobilization by Fluo-4 dye based FLIPR assay | Homo sapiens | 31 | ALA3994633 | cell-based format | Scientific Literature | |
3. | ALA3996977 | Functional | Agonist activity at human FFA4 receptor expressed in human U2OS cells co-expressing Galpha16 assessed as calcium mobilization by Fluo-4 dye based FLIPR assay relative to GSK137647A | Homo sapiens | 30 | ALA3994633 | cell-based format | Scientific Literature | |
4. | ALA3996978 | Functional | Agonist activity at human FFA1 receptor expressed in human U2OS cells co-expressing Galpha16 assessed as calcium mobilization by Fluo-4 dye based FLIPR assay relative to GSK137647A | Homo sapiens | 17 | ALA3994633 | cell-based format | Scientific Literature | |
5. | ALA3996980 | Binding | Selectivity ratio of EC50 for human FFA1 receptor expressed in human U2OS cells co-expressing Galpha16 to EC50 for human FFA4 receptor expressed in human U2OS cells co-expressing Galpha16 | Homo sapiens | 2 | ALA3994633 | cell-based format | Scientific Literature | |
6. | ALA3996982 | ADME | Clearance in C57BL/6J mouse at 4.2 mg/kg, iv | Mus musculus | 1 | ALA3994633 | organism-based format | Scientific Literature | |
7. | ALA3996984 | ADME | AUC in C57BL/6J mouse at 4.2 mg/kg, iv | Mus musculus | 1 | ALA3994633 | organism-based format | Scientific Literature | |
8. | ALA3996985 | ADME | Cmax in C57BL/6J mouse at 10 mg/kg, po | Mus musculus | 5 | ALA3994633 | organism-based format | Scientific Literature | |
9. | ALA3996986 | ADME | AUC in C57BL/6J mouse at 10 mg/kg, po | Mus musculus | 5 | ALA3994633 | organism-based format | Scientific Literature | |
10. | ALA3996987 | ADME | Oral bioavailability in C57BL/6J mouse at 10 mg/kg | Mus musculus | 5 | ALA3994633 | organism-based format | Scientific Literature | |
11. | ALA3996988 | ADME | Half life in C57BL/6J mouse at 10 mg/kg, po | Mus musculus | 1 | ALA3994633 | organism-based format | Scientific Literature | |
12. | ALA3996991 | ADME | Protein binding in human plasma | Homo sapiens | 5 | ALA3994633 | cell-free format | Scientific Literature | |
13. | ALA3996992 | Binding | Agonist activity at mouse FFA4 receptor relative to control | Mus musculus | 1 | ALA3994633 | single protein format | Scientific Literature | |
14. | ALA3996993 | Binding | Agonist activity at mouse FFA4 receptor | Mus musculus | 1 | ALA3994633 | single protein format | Scientific Literature | |
15. | ALA3996994 | Binding | Agonist activity at rat FFA4 receptor | Rattus norvegicus | 1 | ALA3994633 | single protein format | Scientific Literature | |
16. | ALA3996995 | Binding | Agonist activity at rat FFA4 receptor relative to control | Rattus norvegicus | 1 | ALA3994633 | single protein format | Scientific Literature | |
17. | ALA3996996 | Binding | Agonist activity at mouse FFA1 receptor | Mus musculus | 1 | ALA3994633 | single protein format | Scientific Literature | |
18. | ALA3996997 | Binding | Agonist activity at mouse FFA1 receptor relative to control | Mus musculus | 1 | ALA3994633 | single protein format | Scientific Literature | |
19. | ALA3996998 | Binding | Agonist activity at rat FFA1 receptor | Rattus norvegicus | 1 | ALA3994633 | single protein format | Scientific Literature | |
20. | ALA3996999 | Binding | Agonist activity at human FFA2 receptor by FLIPR assay | Homo sapiens | 1 | ALA3994633 | single protein format | Scientific Literature |