# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4009829 | Physicochemical | Stability of the compound in pH 4 buffer solution at 100 uM after 180 hrs by HPLC analysis | 1 | ALA4007447 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA4009831 | ADME | Prodrug activation in human liver microsomes assessed as 2-Amino-N-(2-methoxyphenyl)-6-((4-nitrophenyl)sulfonyl)benzamide formation at 1.5 mg/ml after 10 mins in presence of NADPH by HPLC analysis | Homo sapiens | 1 | ALA4007447 | assay format | Scientific Literature | |
3. | ALA4009832 | ADME | Cytotoxicity against human H9 cells assessed as reduction in cell viability after 7 days by MTT assay | Homo sapiens | 34 | ALA4007447 | cell-based format | Scientific Literature | |
4. | ALA4009833 | Functional | Antiviral activity against HIV1 subtype B NL4-3 infected in human H9 cells assessed as reduction in p24 level after 7 days by ELISA | Human immunodeficiency virus 1 | 34 | ALA4007447 | cell-based format | Scientific Literature | |
5. | ALA4009834 | Unassigned | Therapeutic index, ratio of CC50 for human H9 cells to EC50 for HIV1 subtype B NL4-3 infected in human H9 cells | 34 | ALA4007447 | cell-based format | Scientific Literature | ||
6. | ALA4009846 | Physicochemical | Aqueous solubility in water after 24 to 72 hrs by HPLC based shake flask method | 3 | ALA4007447 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4009847 | Physicochemical | Solubility in methanol after 24 to 72 hrs by HPLC based shake flask method | 3 | ALA4007447 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA4009848 | Physicochemical | Solubility in ethanol after 24 to 72 hrs by HPLC based shake flask method | 3 | ALA4007447 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA4009849 | Physicochemical | Solubility in acetonitrile after 24 to 72 hrs by HPLC based shake flask method | 3 | ALA4007447 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA4009850 | Physicochemical | Solubility in ethylacetate after 24 to 72 hrs by HPLC based shake flask method | 3 | ALA4007447 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4009851 | Physicochemical | Solubility in acetone after 24 to 72 hrs by HPLC based shake flask method | 3 | ALA4007447 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA4009860 | Physicochemical | Stability of the compound in pH 7 buffer solution at 100 uM up to 168 hrs by HPLC analysis | 1 | ALA4007447 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA4009861 | Unassigned | Drug degradation in pH 9 buffer solution at 100 uM after 15 hrs by HPLC analysis | 1 | ALA4007447 | assay format | Scientific Literature | ||
14. | ALA4009862 | ADME | Prodrug activation in human liver microsomes assessed as 2-Amino-N-(2-methoxyphenyl)-6-((4-nitrophenyl)sulfonyl)benzamide formation at 1.5 mg/ml after 15 mins in presence of NADPH by HPLC analysis | Homo sapiens | 1 | ALA4007447 | assay format | Scientific Literature | |
15. | ALA4009863 | ADME | Prodrug activation in human liver microsomes assessed as 2-Amino-N-(2-methoxyphenyl)-6-((4-nitrophenyl)sulfonyl)benzamide formation at 1.5 mg/ml after 20 mins in presence of NADPH by HPLC analysis | Homo sapiens | 1 | ALA4007447 | assay format | Scientific Literature |