| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4016143 | B | Inhibition of COX-mediated PGD2/PGE2 production in arachidonic acid-stimulated RBL1 cells at 10 uM preincubated for 2 hrs followed by A23187 induction for 15 mins by LC/MS/MS analysis relative to control | Rattus norvegicus | 74 | ALA4014332 | assay format | Scientific Literature | |
| 2. | ALA4016144 | B | Inhibition of 5-LOX-mediated LTB4 production in arachidonic acid-stimulated RBL1 cells at 10 uM preincubated for 2 hrs followed by A23187 induction for 15 mins by LC/MS/MS analysis relative to control | Rattus norvegicus | 74 | ALA4014332 | assay format | Scientific Literature | |
| 3. | ALA4016145 | B | Induction of microtubule stabilization in human QBI293 cells assessed as increase in acetylated tubulin levels at 10 uM after 4 hrs by ELISA relative to control | Homo sapiens | 76 | ALA4014332 | cell-based format | Scientific Literature | |
| 4. | ALA4016150 | A | Change in total alpha-tubulin levels in human QBI293 cells at 1 uM after 4 hrs by ELISA relative to control | Homo sapiens | 73 | ALA4014332 | cell-based format | Scientific Literature | |
| 5. | ALA4016151 | B | Inhibition of COX-mediated PGD2/PGE2 production in arachidonic acid-stimulated RBL1 cells preincubated for 2 hrs followed by A23187 induction for 15 mins by LC/MS/MS analysis | Rattus norvegicus | 13 | ALA4014332 | assay format | Scientific Literature | |
| 6. | ALA4016152 | B | Inhibition of 5-LOX-mediated LTB4 production in arachidonic acid-stimulated RBL1 cells preincubated for 2 hrs followed by A23187 induction for 15 mins by LC/MS/MS analysis | Rattus norvegicus | 13 | ALA4014332 | assay format | Scientific Literature | |
| 7. | ALA4016154 | A | Drug uptake in mouse brain at 2 mg/kg, ip administered as cassette dosing after 1 hr by LC-MS/MS method | Mus musculus | 7 | ALA4014332 | organism-based format | Scientific Literature | |
| 8. | ALA4016156 | A | Plasma concentration in mouse at 2 mg/kg, ip administered as cassette dosing after 1 hr by LC-MS/MS method | Mus musculus | 7 | ALA4014332 | organism-based format | Scientific Literature | |
| 9. | ALA4016158 | A | Ratio of drug level in brain to plasma in mouse at 2 mg/kg, ip administered as cassette dosing | Mus musculus | 7 | ALA4014332 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!