| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4019411 | A | Cytotoxicity against human HepG2 cells up to 100 uM after 48 hrs by WST1 assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4019412 | B | Transactivation of FXR in human HepG2 cells assessed as BSEP mRNA expression at 1 uM after 8 to 16 hrs by SYBR green based qRT-PCR analysis relative to DMSO control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA4019413 | B | Transactivation of human FXR expressed in human HeLa cells co-expressing BSEP after 24 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 4. | ALA4019414 | B | Transactivation of human FXR expressed in human HeLa cells co-expressing BSEP at 50 uM after 24 hrs by dual-glo luciferase reporter gene assay relative to GW4064 | Homo sapiens | 55 | cell-based format | Scientific Literature | ||
| 5. | ALA4019416 | B | Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition measured for 30 mins by fluorescence photometric method | Homo sapiens | 39 | single protein format | Scientific Literature | ||
| 6. | ALA4019419 | P | Aqueous solubility of compound at 5 mg after 24 hrs by HPLC analysis | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA4019420 | B | Binding affinity to FXR ligand binding domain (unknown origin) isothermal titration calorimetry assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4019421 | B | Transactivation of human GAL4-fused PPARalpha ligand binding domain expressed in HEL293T cells at 10 uM after 12 to 14 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4019422 | B | Transactivation of human GAL4-fused PPARgamma ligand binding domain expressed in HEL293T cells after 12 to 14 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4019423 | B | Transactivation of human GAL4-fused PPARgamma ligand binding domain expressed in HEL293T cells at 10 uM after 12 to 14 hrs by dual-glo luciferase reporter gene assay relative to pioglitazone | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4019424 | B | Transactivation of human GAL4-fused PPARdelta ligand binding domain expressed in HEL293T cells at 10 uM after 12 to 14 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4019425 | B | Transactivation of human GAL4-fused RXRalpha ligand binding domain expressed in HEL293T cells at 10 uM after 12 to 14 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4019426 | B | Transactivation of human GAL4-fused LXRbeta ligand binding domain expressed in HEL293T cells at 10 uM after 12 to 14 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4019427 | B | Transactivation of human GAL4-fused RXRbeta ligand binding domain expressed in HEL293T cells at 10 uM after 12 to 14 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4019428 | B | Transactivation of human GAL4-fused RXRgamma ligand binding domain expressed in HEL293T cells at 10 uM after 12 to 14 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4019429 | B | Transactivation of human GAL4-fused RARalpha ligand binding domain expressed in HEL293T cells at 10 uM after 12 to 14 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4019430 | B | Transactivation of human GAL4-fused RARbeta ligand binding domain expressed in HEL293T cells at 10 uM after 12 to 14 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4019431 | B | Transactivation of human GAL4-fused RARgamma ligand binding domain expressed in HEL293T cells at 10 uM after 12 to 14 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4019432 | B | Transactivation of human GAL4-fused VDR ligand binding domain expressed in HEL293T cells at 10 uM after 12 to 14 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4019433 | B | Transactivation of human GAL4-fused CAR ligand binding domain expressed in HEL293T cells at 10 uM after 12 to 14 hrs by dual-Glo luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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