# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4055361 | Binding | Displacement of (5-(6-(10H-spiro(1-benzofuran-3,30-pyrrolidin)-10-yl)pyridazin-3-yl)-1,2,4-oxadiazol-3-yl)[3H2]methanol from SCD1 in human liver microsomes after 120 mins TopCount liquid scintillation counting method | Homo sapiens | 17 | ALA4052653 | assay format | Scientific Literature | |
2. | ALA4055362 | ADME | Fraction unbound in mouse plasma | Mus musculus | 4 | ALA4052653 | cell-free format | Scientific Literature | |
3. | ALA4055363 | Functional | Growth inhibition of human HCT116 cells after 72 hrs by CellTiter-Glo luminescence assay | Homo sapiens | 17 | ALA4052653 | cell-based format | Scientific Literature | |
4. | ALA4055364 | ADME | Stability in human liver microsomes | Homo sapiens | 10 | ALA4052653 | assay format | Scientific Literature | |
5. | ALA4055365 | ADME | Stability in mouse liver microsomes | Mus musculus | 10 | ALA4052653 | assay format | Scientific Literature | |
6. | ALA4055366 | ADME | Total clearance in mouse at 0.1 mg/kg, iv or 1 mg/kg, po administered as cassette dose | Mus musculus | 4 | ALA4052653 | organism-based format | Scientific Literature | |
7. | ALA4055367 | ADME | AUC in po dosed mouse administered as cassette dose | Mus musculus | 4 | ALA4052653 | organism-based format | Scientific Literature | |
8. | ALA4055368 | ADME | Mean residence time in po dosed mouse administered as cassette dose | Mus musculus | 4 | ALA4052653 | organism-based format | Scientific Literature |