# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4051081 | ADME | Drug metabolism in human KB cells assessed as formation of protoporphyrin 9 after 2 to 24 hrs by fluorescence spectrometer | Homo sapiens | 2 | ALA4049424 | cell-based format | Scientific Literature | |
2. | ALA4051082 | ADME | Drug metabolism in human KB cells assessed as protoporphyrin 9 formation at 500 uM preincubated for 1 hr at 4 degC followed by compound washout and subsequent incubation for 4 hrs at 37 degC by fluorescence spectrometer | Homo sapiens | 8 | ALA4049424 | cell-based format | Scientific Literature | |
3. | ALA4051085 | ADME | Drug metabolism in human KB cells assessed as formation of protoporphyrin 9 at 100 uM after 6 to 24 hrs by fluorescence spectrometer | Homo sapiens | 5 | ALA4049424 | cell-based format | Scientific Literature | |
4. | ALA4051087 | Functional | Phototoxicity in human KB cells assessed as reduction in cell viability preincubated for 4 hrs followed by irradiation with blue light at 2.5 J/cm2 and subsequent incubation for 18 hrs measured after 24 hrs post treatment by MTT assay | Homo sapiens | 12 | ALA4049424 | cell-based format | Scientific Literature | |
5. | ALA4051088 | Functional | Phototoxicity in human MCF7 cells assessed as reduction in cell viability preincubated for 4 hrs followed by irradiation with blue light at 2.5 J/cm2 and subsequent incubation for 18 hrs measured after 24 hrs post treatment by MTT assay | Homo sapiens | 12 | ALA4049424 | cell-based format | Scientific Literature | |
6. | ALA4051089 | Functional | Phototoxicity in human doxorubicin resistant MCF7/R cells assessed as reduction in cell viability preincubated for 4 hrs followed by irradiation with blue light at 2.5 J/cm2 and subsequent incubation for 18 hrs measured after 24 hrs post treatment by MTT assay | Homo sapiens | 12 | ALA4049424 | cell-based format | Scientific Literature | |
7. | ALA4051094 | Toxicity | Dark toxicity against human KB cells at 200 uM preincubated for 4 hrs followed by compound washout measured after 24 hrs by MTT assay | Homo sapiens | 10 | ALA4049424 | cell-based format | Scientific Literature | |
8. | ALA4051098 | ADME | Drug metabolism in human KB cells assessed as formation of protoporphyrin 9 preincubated for 2 hrs followed by compound washout measured after 24 hrs by HPLC-based fluorescence analysis | Homo sapiens | 6 | ALA4049424 | cell-based format | Scientific Literature | |
9. | ALA4051099 | ADME | Drug metabolism in human doxorubicin resistant MCF7/R cells assessed as formation of protoporphyrin 9 preincubated for 2 hrs followed by compound washout measured after 24 hrs by HPLC-based fluorescence analysis | Homo sapiens | 6 | ALA4049424 | cell-based format | Scientific Literature | |
10. | ALA4051103 | ADME | Drug metabolism in human doxorubicin resistant MCF7/R cells assessed as formation of protoporphyrin 9 at 100 uM after 6 hrs by fluorescence spectrometer relative to ALA | Homo sapiens | 1 | ALA4049424 | cell-based format | Scientific Literature | |
11. | ALA4051107 | Toxicity | Dark toxicity against human KB cells assessed as cell survival at 100 uM after 24 hrs by MTT assay | Homo sapiens | 10 | ALA4049424 | cell-based format | Scientific Literature |