| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4008765 | B | Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using biotinylated H3K4me1 peptide as substrate preincubated for 10 mins with enzyme followed by substrate addition measured after 1 hr by TR-FRET HTS assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 2. | ALA4008766 | B | Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using biotinylated H3K4me1 peptide as substrate preincubated for 20 mins measured after 1 hr by TR-FRET assay | Homo sapiens | 59 | assay format | Scientific Literature | ||
| 3. | ALA4008767 | B | Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using H3K4me1 peptide as substrate preincubated for 15 mins with enzyme followed by substrate addition measured after 12 mins by Amplex Ultra Red reagent based HRP enzyme coupled assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 4. | ALA4008769 | B | Reversible inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using H3K4me1 peptide as substrate preincubated for 15 mins with enzyme followed by substrate addition by jump dilution based HRP enzyme coupled assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 5. | ALA4008770 | B | Non-competitive inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using H3K4me1 peptide as substrate preincubated for 15 mins followed by substrate addition measured for 12 mins by Lineweaver-Burk plot analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA4008772 | B | Inhibition of KDM1B (unknown origin) | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 7. | ALA4008773 | B | Inhibition of recombinant human MAOA incubated for 15 mins measured after 30 mins by luminescence-Glo assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 8. | ALA4008774 | B | Inhibition of recombinant human MAOB incubated for 15 mins measured after 30 mins by luminescence-Glo assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 9. | ALA4008775 | B | Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli assessed as Vmax for substrate using H3K4me1 as substrate preincubated for 15 mins followed by substrate addition measured for 12 mins by Lineweaver-Burk plot analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 10. | ALA4008776 | B | Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli assessed as Km for substrate using H3K4me1 peptide as substrate preincubated for 15 mins followed by substrate addition measured for 12 mins by Lineweaver-Burk plot analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 11. | ALA4008777 | B | Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli at 10 uM using biotinylated H3K4me1 peptide as substrate preincubated for 10 mins with enzyme followed by substrate addition measured after 1 hr by TR-FRET HTS assay | Homo sapiens | 23 | assay format | Scientific Literature | ||
| 12. | ALA4008790 | B | Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as substrate incubated for 20 mins measured after 1 hr by TR-FRET assay | Homo sapiens | 53 | assay format | Scientific Literature | ||
| 13. | ALA5224065 | B | Inhibition of LSD1 (unknown origin) | Homo sapiens | 40 | single protein format | Scientific Literature |
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