# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4041722 | ADME | Displacement of [3H]prazosin from recombinant human alpha-1b adrenergic receptor expressed in CHO cell membranes after 30 mins by liquid scintillation counting method | Homo sapiens | 9 | ALA4041469 | cell-based format | Scientific Literature | |
2. | ALA4041723 | ADME | Displacement of [3H]prazosin from recombinant human alpha-1a adrenergic receptor expressed in CHO cell membranes after 30 mins by liquid scintillation counting method | Homo sapiens | 9 | ALA4041469 | cell-based format | Scientific Literature | |
3. | ALA4041724 | ADME | Displacement of [3H]prazosin from recombinant human alpha-1d adrenergic receptor expressed in CHO cell membranes after 30 mins by liquid scintillation counting method | Homo sapiens | 10 | ALA4041469 | cell-based format | Scientific Literature | |
4. | ALA4041725 | Binding | Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation counting method | Homo sapiens | 32 | ALA4041469 | cell-based format | Scientific Literature | |
5. | ALA4041726 | Functional | Agonist activity at recombinant human 5HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding preincubated for 20 mins followed by [35S]GTPgammaS addition measured after 30 mins by liquid scintillation counting method | Homo sapiens | 19 | ALA4041469 | cell-based format | Scientific Literature | |
6. | ALA4041727 | Functional | Agonist activity at recombinant human 5HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding up to 10 uM preincubated for 20 mins followed by [35S]GTPgammaS addition measured after 30 mins by liquid scintillation counting method relative to 5-HT | Homo sapiens | 19 | ALA4041469 | cell-based format | Scientific Literature |