| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4011522 | B | Inhibition of full length GST-tagged PDE1B (unknown origin) assessed as decrease in FAM-cAMP hydrolysis preincubated for 5 mins followed by FAM-cAMP addition measured after 30 mins by IMAP assay | Homo sapiens | 15 | ALA4007512 | single protein format | Scientific Literature | |
| 2. | ALA4011523 | B | Inhibition of PDE2A1 (unknown origin) assessed as decrease in FAM-cAMP hydrolysis preincubated for 5 mins followed by FAM-cAMP addition measured after 30 mins by IMAP assay | Homo sapiens | 2 | ALA4007512 | single protein format | Scientific Literature | |
| 3. | ALA4011524 | B | Inhibition of PDE3A (unknown origin) assessed as decrease in FAM-cAMP hydrolysis preincubated for 5 mins followed by FAM-cAMP addition measured after 30 mins by IMAP assay | Homo sapiens | 2 | ALA4007512 | single protein format | Scientific Literature | |
| 4. | ALA4011525 | B | Inhibition of PDE4D3 (unknown origin) assessed as decrease in FAM-cAMP hydrolysis preincubated for 5 mins followed by FAM-cAMP addition measured after 30 mins by IMAP assay | Homo sapiens | 2 | ALA4007512 | single protein format | Scientific Literature | |
| 5. | ALA4011526 | B | Inhibition of N-terminal GST-tagged full length recombinant human PDE5A1 expressed in Baculovirus infected Sf9 insect cells assessed as decrease in FAM-cGMP hydrolysis after 1 hr by fluorescence polarization assay | Homo sapiens | 2 | ALA4007512 | cell-based format | Scientific Literature | |
| 6. | ALA4011527 | B | Inhibition of N-terminal GST-tagged full length recombinant human PDE6C expressed in Baculovirus infected Sf9 insect cells | Homo sapiens | 2 | ALA4007512 | cell-based format | Scientific Literature | |
| 7. | ALA4011528 | B | Inhibition of N-terminal GST-tagged recombinant human PDE7A1 (122-end residues) expressed in Baculovirus infected Sf9 insect cells assessed as decrease in FAM-cAMP hydrolysis after 1 hr by fluorescence polarization assay | Homo sapiens | 2 | ALA4007512 | cell-based format | Scientific Literature | |
| 8. | ALA4011529 | B | Inhibition of N-terminal GST-tagged full length recombinant human PDE8A1 expressed in Baculovirus infected Sf9 insect cells assessed as decrease in FAM-cAMP hydrolysis after 1 hr by fluorescence polarization assay | Homo sapiens | 2 | ALA4007512 | cell-based format | Scientific Literature | |
| 9. | ALA4011530 | B | Inhibition of N-terminal GST-tagged full length recombinant human PDE9A2 expressed in Baculovirus infected Sf9 insect cells assessed as decrease in FAM-cGMP hydrolysis after 1 hr by fluorescence polarization assay | Homo sapiens | 2 | ALA4007512 | cell-based format | Scientific Literature | |
| 10. | ALA4011531 | B | Inhibition of PDE10A1 (unknown origin) assessed as decrease in FAM-cAMP hydrolysis after 1 hr by IMAP assay | Homo sapiens | 15 | ALA4007512 | single protein format | Scientific Literature | |
| 11. | ALA4011532 | B | Inhibition of N-terminal GST-tagged full length recombinant human PDE11A4 expressed in Baculovirus infected Sf9 insect cells assessed as decrease in FAM-cAMP hydrolysis after 1 hr by fluorescence polarization assay | Homo sapiens | 2 | ALA4007512 | cell-based format | Scientific Literature | |
| 12. | ALA4011533 | B | Selectivity ratio of IC50 for PDE2A1 (unknown origin) to IC50 for full length GST-tagged PDE1B (unknown origin) | Homo sapiens | 2 | ALA4007512 | assay format | Scientific Literature | |
| 13. | ALA4011534 | B | Selectivity ratio of IC50 for PDE3A (unknown origin) to IC50 for full length GST-tagged PDE1B (unknown origin) | Homo sapiens | 2 | ALA4007512 | assay format | Scientific Literature | |
| 14. | ALA4011535 | B | Selectivity ratio of IC50 for PDE4D3 (unknown origin) to IC50 for full length GST-tagged PDE1B (unknown origin) | Homo sapiens | 2 | ALA4007512 | assay format | Scientific Literature | |
| 15. | ALA4011536 | B | Selectivity ratio of IC50 for N-terminal GST-tagged full length recombinant human PDE5A1 to IC50 for full length GST-tagged PDE1B (unknown origin) | Homo sapiens | 2 | ALA4007512 | assay format | Scientific Literature | |
| 16. | ALA4011537 | B | Selectivity ratio of IC50 for N-terminal GST-tagged full length recombinant human PDE6C to IC50 for full length GST-tagged PDE1B (unknown origin) | Homo sapiens | 2 | ALA4007512 | assay format | Scientific Literature | |
| 17. | ALA4011538 | B | Selectivity ratio of IC50 for N-terminal GST-tagged recombinant human PDE7A1 (122-end residues) to IC50 for full length GST-tagged PDE1B (unknown origin) | Homo sapiens | 2 | ALA4007512 | assay format | Scientific Literature | |
| 18. | ALA4011539 | B | Selectivity ratio of IC50 for N-terminal GST-tagged full length recombinant human PDE8A1 to IC50 for full length GST-tagged PDE1B (unknown origin) | Homo sapiens | 2 | ALA4007512 | assay format | Scientific Literature | |
| 19. | ALA4011540 | B | Selectivity ratio of IC50 for N-terminal GST-tagged full length recombinant human PDE9A2 to IC50 for full length GST-tagged PDE1B (unknown origin) | Homo sapiens | 2 | ALA4007512 | assay format | Scientific Literature | |
| 20. | ALA4011541 | B | Selectivity ratio of IC50 for PDE10A1 (unknown origin) to IC50 for full length GST-tagged PDE1B (unknown origin) | Homo sapiens | 2 | ALA4007512 | assay format | Scientific Literature |
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