# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3999523 | F | Antioxidant activity in FRDA patient derived lymphocytes assessed as inhibition of DEM-mediated lipid peroxidation at 0.1 to 2.5 uM pretreated for 16 hrs followed by DEM addition measured after 120 mins by C11-BODIPY581/591 probe-based FACS analysis | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
2. | ALA3999530 | F | Cytoprotective activity in FRDA patient derived lymphocytes cultured in glucose-free media supplemented with galactose assessed as total intracellular ATP levels at 1 uM after 48 hrs by luciferin-luciferase reaction-based bioluminescence assay relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
3. | ALA3999531 | F | Cytoprotective activity in FRDA patient derived lymphocytes cultured in glucose-free media supplemented with galactose assessed as total intracellular ATP levels at 5 uM after 48 hrs by luciferin-luciferase reaction-based bioluminescence assay relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
4. | ALA3999532 | F | Cytoprotective activity in FRDA patient derived lymphocytes cultured in glucose-free media supplemented with galactose assessed as total intracellular ATP levels at 20 uM after 48 hrs by luciferin-luciferase reaction-based bioluminescence assay relative to control | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
5. | ALA3999534 | A | Metabolic stability in bovine liver microsomes assessed as compound recovery at 25 uM after 30 mins in presence of beta-NADPH by HPLC method | Bos taurus | 9 | assay format | Scientific Literature |