| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4037917 | B | Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPilight pyrophosphate-detection based assay | Homo sapiens | 34 | single protein format | Scientific Literature | ||
| 2. | ALA4037918 | P | Solubility of the compound in buffer | 34 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4037919 | A | Intrinsic clearance in mouse liver microsomes at 1 mM preincubated for 5 mins followed by NADPH addition measured by LC-MS/MS analysis | Mus musculus | 17 | assay format | Scientific Literature | ||
| 4. | ALA4037920 | A | Drug metabolism in mouse liver microsomes at 1 mM preincubated for 5 mins followed by NADPH addition measured after 30 mins by LC-MS/MS analysis | Mus musculus | 17 | assay format | Scientific Literature | ||
| 5. | ALA4037924 | A | Apparent permeability across apical to basolateral side in human Caco2 cells at 2 uM after 2 hrs by LC-MS/MS analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA4037925 | A | Apparent permeability across basolateral to apical side in human Caco2 cells at 2 uM after 2 hrs by LC-MS/MS analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4037926 | A | Efflux ratio of apparent permeability in human Caco2 cells at 2 uM after 2 hrs by LC-MS/MS analysis | Homo sapiens | 4 | cell-based format | Scientific Literature |
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