| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4035636 | F | Effect on RelB protein expression in human THP1 cells at 10 uM after 3 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4035637 | B | Antagonist activity at TLR4 (unknown origin) expressed in human AD293 cells assessed as inhibition of LPS/ATP-stimulated TLR4/NF-kB signaling pathway after 16 hrs by luciferase reporter gene assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA4035639 | B | Inhibition of TNFalpha-stimulated NF-kB signaling pathway (unknown origin) expressed in human AD293 cells after 4 hrs by luciferase reporter gene assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA4035640 | A | Cytotoxicity against human AD293 cells assessed as reduction in cell viability after 24 hrs by methylene blue dye based spectrophotometric method | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 5. | ALA4035648 | B | Antagonist activity at TLR4 in human THP1 cells assessed as inhibition of LPS-stimulated IL-6 mRNA level at 10 uM after 16 hrs by RT-PCR method | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 6. | ALA4035649 | B | Antagonist activity at TLR4 in human THP1 cells assessed as inhibition of LPS-stimulated RANTES mRNA level at 10 uM after 16 hrs by RT-PCR method | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA4035650 | B | Antagonist activity at TLR3 in human THP1 cells assessed as inhibition of poly IC-stimulated IL-6 mRNA level at 10 uM after 16 hrs by RT-PCR method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4035651 | B | Antagonist activity at TLR3 in human THP1 cells assessed as inhibition of poly IC-stimulated RANTES mRNA level at 10 uM after 16 hrs by RT-PCR method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4035652 | B | Antagonist activity at TLR2 in human THP1 cells assessed as inhibition of PGN-stimulated IL-6 mRNA level at 10 uM after 16 hrs by RT-PCR method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4035653 | B | Antagonist activity at TLR2 in human THP1 cells assessed as inhibition of PGN-stimulated RANTES mRNA level at 10 uM after 16 hrs by RT-PCR method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4035654 | B | Antagonist activity at TLR4 in human THP1 cells assessed as inhibition of LPS-stimulated IL-1beta level at 10 uM by bead based immunoassay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4035655 | B | Antagonist activity at TLR4 in human THP1 cells assessed as inhibition of LPS-stimulated TNFalpha level at 10 uM by bead based immunoassay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA4035656 | B | Antagonist activity at TLR4 in human THP1 cells assessed as inhibition of LPS-stimulated IL-6 level at 10 uM by bead based immunoassay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA4035657 | B | Antagonist activity at TLR3 in human THP1 cells assessed as inhibition of poly IC-stimulated IL-1beta level at 10 uM by bead based immunoassay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4035658 | B | Antagonist activity at TLR3 in human THP1 cells assessed as inhibition of poly IC-stimulated TNFalpha level at 10 uM by bead based immunoassay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4035659 | B | Antagonist activity at TLR2 in human THP1 cells assessed as inhibition of PGN-stimulated IL-1beta level at 10 uM by bead based immunoassay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4035660 | B | Antagonist activity at TLR2 in human THP1 cells assessed as inhibition of PGN-stimulated TNFalpha level at 10 uM by bead based immunoassay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA4035661 | B | Inhibition of TNFalpha-stimulated NF-kB p65 activation (unknown origin) expressed in human AD293 cells assessed as nuclear translocation of p65 at 10 uM after 3 hrs by confocal microscopic method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA4035662 | B | Inhibition of TNFalpha-stimulated NF-kB p65 phosphorylation (unknown origin) expressed in human AD293 cells at 10 uM after 3 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA4035663 | B | Inhibition of TNFalpha-stimulated IkBalpha phosphorylation in human AD293 cells at 10 uM after 3 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature |
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