| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4012199 | ADME | Unbound clearance in rat at 0.5 mg/kg, iv | Rattus norvegicus | 8 | ALA4011598 | organism-based format | Scientific Literature | |
| 2. | ALA4012201 | Binding | Inhibition of human Nav1.5 expressed in HEK293 cells assessed as reduction in peak inward current by ionworks quattro electrophysiology assay | Homo sapiens | 23 | ALA4011598 | cell-based format | Scientific Literature | |
| 3. | ALA4012206 | ADME | Unbound clearance in dog at 0.25 mg/kg, iv | Canis lupus familiaris | 10 | ALA4011598 | organism-based format | Scientific Literature | |
| 4. | ALA4012207 | ADME | Intrinsic clearance in human liver microsomes at 1 uM after 1 to 40 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 21 | ALA4011598 | assay format | Scientific Literature | |
| 5. | ALA4012208 | ADME | Intrinsic clearance in rat liver microsomes at 1 uM after 1 to 40 mins in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 21 | ALA4011598 | assay format | Scientific Literature | |
| 6. | ALA4012209 | ADME | Activation of human PXR at 10 uM in presence of rifampicin | Homo sapiens | 24 | ALA4011598 | single protein format | Scientific Literature | |
| 7. | ALA4012210 | ADME | Total clearance in rat at 0.5 mg/kg, iv | Rattus norvegicus | 8 | ALA4011598 | organism-based format | Scientific Literature | |
| 8. | ALA4012211 | ADME | Total clearance in dog at 0.25 mg/kg, iv | Canis lupus familiaris | 10 | ALA4011598 | organism-based format | Scientific Literature | |
| 9. | ALA4012237 | Binding | Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 3 to 5 mins at -125 mV holding potential by electrophysiology assay | Homo sapiens | 27 | ALA4011598 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!