# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4050423 | B | Inhibition of EGFR L858R mutant in human H3255 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay | Homo sapiens | 4 | ALA4049404 | cell-based format | Scientific Literature | |
2. | ALA4050424 | B | Inhibition of EGFR exon 19 deletion mutant in human PC9 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay | Homo sapiens | 4 | ALA4049404 | cell-based format | Scientific Literature | |
3. | ALA4050425 | B | Inhibition of Tel-fused EGFR T790M mutant (unknown origin) expressed in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay | Homo sapiens | 23 | ALA4049404 | cell-based format | Scientific Literature | |
4. | ALA4050426 | A | Growth inhibition of mouse BAF3 cells after 72 hrs by CellTiter-Glo assay | Mus musculus | 27 | ALA4049404 | cell-based format | Scientific Literature | |
5. | ALA4050427 | A | Inhibition of Tel-fused EGFR (unknown origin) expressed in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4049404 | cell-based format | Scientific Literature | |
6. | ALA4050428 | B | Inhibition of Tel-fused EGFR C797S mutant (unknown origin) expressed in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4049404 | cell-based format | Scientific Literature | |
7. | ALA4050429 | B | Inhibition of Tel-fused EGFR L858R mutant (unknown origin) expressed in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4049404 | cell-based format | Scientific Literature | |
8. | ALA4050430 | B | Inhibition of Tel-fused EGFR L858R/C797S mutant (unknown origin) expressed in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4049404 | cell-based format | Scientific Literature | |
9. | ALA4050431 | B | Inhibition of Tel-fused EGFR T790M/C797S mutant (unknown origin) expressed in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4049404 | cell-based format | Scientific Literature | |
10. | ALA4050432 | B | Inhibition of full length EGFR exon 19 deletion mutant (unknown origin) expressed in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4049404 | cell-based format | Scientific Literature | |
11. | ALA4050433 | B | Inhibition of full length EGFR T790M/L858R mutant (unknown origin) expressed in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4049404 | cell-based format | Scientific Literature | |
12. | ALA4050434 | B | Inhibition of full length EGFR T790M/L858R/C797S mutant (unknown origin) expressed in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4049404 | cell-based format | Scientific Literature | |
13. | ALA4050435 | A | Binding affinity to wild-type human EGFR expressed in bacterial system assessed as control score at 1 uM by KINOMEScan assay | Homo sapiens | 1 | ALA4049404 | assay format | Scientific Literature | |
14. | ALA4050436 | B | Binding affinity to human EGFR E746-A750 deletion mutant expressed in bacterial system assessed as control score at 1 uM by KINOMEScan assay | Homo sapiens | 1 | ALA4049404 | assay format | Scientific Literature | |
15. | ALA4050437 | B | Binding affinity to human EGFR G719C mutant expressed in bacterial system assessed as control score at 1 uM by KINOMEScan assay | Homo sapiens | 1 | ALA4049404 | assay format | Scientific Literature | |
16. | ALA4050438 | B | Binding affinity to human EGFR G719S mutant expressed in bacterial system assessed as control score at 1 uM by KINOMEScan assay | Homo sapiens | 1 | ALA4049404 | assay format | Scientific Literature | |
17. | ALA4050439 | B | Binding affinity to human EGFR L747-E749del/A750P mutant expressed in bacterial system assessed as control score at 1 uM by KINOMEScan assay | Homo sapiens | 1 | ALA4049404 | assay format | Scientific Literature | |
18. | ALA4050440 | B | Binding affinity to human EGFR L747-S752del/P753S mutant expressed in bacterial system assessed as control score at 1 uM by KINOMEScan assay | Homo sapiens | 1 | ALA4049404 | assay format | Scientific Literature | |
19. | ALA4050441 | B | Binding affinity to human EGFR L747-T751del/Sins mutant expressed in bacterial system assessed as control score at 1 uM by KINOMEScan assay relative to control | Homo sapiens | 1 | ALA4049404 | assay format | Scientific Literature | |
20. | ALA4050442 | B | Binding affinity to human EGFR L858R mutant expressed in bacterial system assessed as control score at 1 uM by KINOMEScan assay | Homo sapiens | 1 | ALA4049404 | assay format | Scientific Literature |