# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3998487 | Binding | Antagonist activity at recombinant human glycine receptor alpha 1 expressed in human tsA201 cells assessed as inhibition of glycine-induced receptor activation after 30 mins by FLIPR membrane potential blue assay | Homo sapiens | 17 | ALA3997776 | cell-based format | Scientific Literature | |
2. | ALA3998488 | Binding | Antagonist activity at recombinant human glycine receptor alpha 1 beta expressed in human tsA201 cells assessed as inhibition of glycine-induced receptor activation after 30 mins by FLIPR membrane potential blue assay | Homo sapiens | 17 | ALA3997776 | cell-based format | Scientific Literature | |
3. | ALA3998489 | Binding | Antagonist activity at recombinant human glycine receptor alpha 1 expressed in HEK293 cells assessed as inhibition of glycine-induced current at -50 mV holding potential by whole cell patch-clamp method | Homo sapiens | 9 | ALA3997776 | cell-based format | Scientific Literature | |
4. | ALA3998490 | Binding | Antagonist activity at recombinant human glycine receptor alpha 1 beta expressed in HEK293 cells assessed as inhibition of glycine-induced current at -50mV holding potential by whole cell patch-clamp method | Homo sapiens | 9 | ALA3997776 | cell-based format | Scientific Literature | |
5. | ALA3998492 | Binding | Displacement of [3H]strychnine from recombinant human glycine receptor alpha 1 expressed in HEK293 cell membranes after 30 mins by liquid scintillation counting method | Homo sapiens | 6 | ALA3997776 | cell-based format | Scientific Literature | |
6. | ALA3998493 | Binding | Selectivity ratio of IC50 for recombinant human glycine receptor alpha 1 beta expressed in human tsA201 cells to IC50 for recombinant human glycine receptor alpha 1 expressed in human tsA201 cells | Homo sapiens | 4 | ALA3997776 | cell-based format | Scientific Literature |