| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3998487 | B | Antagonist activity at recombinant human glycine receptor alpha 1 expressed in human tsA201 cells assessed as inhibition of glycine-induced receptor activation after 30 mins by FLIPR membrane potential blue assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 2. | ALA3998488 | B | Antagonist activity at recombinant human glycine receptor alpha 1 beta expressed in human tsA201 cells assessed as inhibition of glycine-induced receptor activation after 30 mins by FLIPR membrane potential blue assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 3. | ALA3998489 | B | Antagonist activity at recombinant human glycine receptor alpha 1 expressed in HEK293 cells assessed as inhibition of glycine-induced current at -50 mV holding potential by whole cell patch-clamp method | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 4. | ALA3998490 | B | Antagonist activity at recombinant human glycine receptor alpha 1 beta expressed in HEK293 cells assessed as inhibition of glycine-induced current at -50mV holding potential by whole cell patch-clamp method | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 5. | ALA3998492 | B | Displacement of [3H]strychnine from recombinant human glycine receptor alpha 1 expressed in HEK293 cell membranes after 30 mins by liquid scintillation counting method | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 6. | ALA3998493 | B | Selectivity ratio of IC50 for recombinant human glycine receptor alpha 1 beta expressed in human tsA201 cells to IC50 for recombinant human glycine receptor alpha 1 expressed in human tsA201 cells | Homo sapiens | 4 | cell-based format | Scientific Literature |
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