| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4034607 | F | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay | Homo sapiens | 1 | ALA4033641 | cell-based format | Scientific Literature | |
| 2. | ALA4034608 | B | Inhibition of DNMT1 (unknown origin) at 100 uM using poly(dI-dC).poly(dI-dC) as substrate preincubated for 15 mins followed by substrate/[3H]-SAM addition measured after 120 mins by liquid scintillation counting analysis | Homo sapiens | 12 | ALA4033641 | single protein format | Scientific Literature | |
| 3. | ALA4034609 | B | Inhibition of DNMT3A/3L (unknown origin) at 100 uM using biotinylated DNA oligonucleotides as substrate preincubated for 15 mins followed by substrate/[3H]-SAM addition measured after 4 hrs by liquid scintillation counting analysis | Homo sapiens | 12 | ALA4033641 | protein complex format | Scientific Literature | |
| 4. | ALA4034610 | B | Inhibition of DNMT3B/3L (unknown origin) at 100 uM using biotinylated DNA oligonucleotides as substrate preincubated for 15 mins followed by substrate/[3H]-SAM addition measured after 4 hrs by liquid scintillation counting analysis | Homo sapiens | 12 | ALA4033641 | protein complex format | Scientific Literature | |
| 5. | ALA4034611 | B | Inhibition of HDAC1 (unknown origin) preincubated for 15 mins followed by substrate addition measured after 60 mins by fluorescence assay | Homo sapiens | 12 | ALA4033641 | single protein format | Scientific Literature | |
| 6. | ALA4034612 | B | Inhibition of HDAC6 (unknown origin) preincubated for 15 mins followed by substrate addition measured after 60 mins by fluorescence assay | Homo sapiens | 12 | ALA4033641 | single protein format | Scientific Literature | |
| 7. | ALA4034613 | F | Antiproliferative activity against human K562 cells after 72 hrs by MTT assay | Homo sapiens | 13 | ALA4033641 | cell-based format | Scientific Literature | |
| 8. | ALA4034614 | F | Antiproliferative activity against human U937 cells after 72 hrs by MTT assay | Homo sapiens | 12 | ALA4033641 | cell-based format | Scientific Literature | |
| 9. | ALA4034615 | F | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay | Homo sapiens | 1 | ALA4033641 | cell-based format | Scientific Literature | |
| 10. | ALA4034616 | F | Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay | Homo sapiens | 1 | ALA4033641 | cell-based format | Scientific Literature | |
| 11. | ALA4034617 | F | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay | Homo sapiens | 1 | ALA4033641 | cell-based format | Scientific Literature | |
| 12. | ALA4034618 | F | Induction of apoptosis in human U937 cells assessed as viable cells at 0.5 uM after 48 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 99.6%) | Homo sapiens | 1 | ALA4033641 | cell-based format | Scientific Literature | |
| 13. | ALA4034619 | F | Induction of apoptosis in human U937 cells assessed as early apoptotic cells at 0.5 uM after 48 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 0.140%) | Homo sapiens | 1 | ALA4033641 | cell-based format | Scientific Literature | |
| 14. | ALA4034620 | F | Induction of apoptosis in human U937 cells assessed as late apoptotic cells at 0.5 uM after 48 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 0.279%) | Homo sapiens | 1 | ALA4033641 | cell-based format | Scientific Literature | |
| 15. | ALA4034621 | F | Induction of apoptosis in human U937 cells assessed as necrotic cells at 0.5 uM after 48 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 0%) | Homo sapiens | 1 | ALA4033641 | cell-based format | Scientific Literature | |
| 16. | ALA4034622 | F | Induction of apoptosis in human U937 cells assessed as viable cells at 1 uM after 48 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 99.6%) | Homo sapiens | 1 | ALA4033641 | cell-based format | Scientific Literature | |
| 17. | ALA4034623 | F | Induction of apoptosis in human U937 cells assessed as early apoptotic cells at 1 uM after 48 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 0.140%) | Homo sapiens | 1 | ALA4033641 | cell-based format | Scientific Literature | |
| 18. | ALA4034624 | F | Induction of apoptosis in human U937 cells assessed as late apoptotic cells at 1 uM after 48 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 0.279%) | Homo sapiens | 1 | ALA4033641 | cell-based format | Scientific Literature | |
| 19. | ALA4034625 | F | Induction of apoptosis in human U937 cells assessed as necrotic cells at 1 uM after 48 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 0%) | Homo sapiens | 1 | ALA4033641 | cell-based format | Scientific Literature | |
| 20. | ALA4034626 | F | Induction of apoptosis in human U937 cells assessed as viable cells at 2.5 uM after 48 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 99.6%) | Homo sapiens | 1 | ALA4033641 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!