| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4021691 | A | Ratio of drug level in brain to plasma in rat | Rattus norvegicus | 1 | ALA4020748 | assay format | Scientific Literature | |
| 2. | ALA4021692 | B | Activity at Cav1.2 (unknown origin) | Homo sapiens | 1 | ALA4020748 | single protein format | Scientific Literature | |
| 3. | ALA4021695 | U | Selectivity ratio of IC50 for human Nav1.5alpha expressed in HEK293 cells to human Nav1.7alpha expressed in HEK293 cells | Homo sapiens | 12 | ALA4020748 | cell-based format | Scientific Literature | |
| 4. | ALA4021696 | B | Inhibition of NaV1.7 channel in human DRG neurons assessed as reduction of TTX-sensitive current by whole cell patch clamp assay | Homo sapiens | 1 | ALA4020748 | assay format | Scientific Literature | |
| 5. | ALA4021697 | B | Inhibition of NaV1.7 channel in mouse DRG neurons assessed as reduction of TTX-sensitive current by whole cell patch clamp assay | Mus musculus | 1 | ALA4020748 | assay format | Scientific Literature | |
| 6. | ALA4021698 | B | Inhibition of NaV1.7 channel in rat DRG neurons assessed as reduction of TTX-sensitive sodium current by whole cell patch clamp assay | Rattus norvegicus | 1 | ALA4020748 | assay format | Scientific Literature | |
| 7. | ALA4021699 | A | Activity at PXR (unknown origin) | Homo sapiens | 1 | ALA4020748 | single protein format | Scientific Literature | |
| 8. | ALA4021700 | B | Activity at human ERG | Homo sapiens | 1 | ALA4020748 | single protein format | Scientific Literature | |
| 9. | ALA4021701 | A | Ratio of drug level in CSF to plasma in rat | Rattus norvegicus | 1 | ALA4020748 | assay format | Scientific Literature | |
| 10. | ALA4021702 | A | Unbound plasma clearance in Wistar Hannover rat at 2 mg/kg, iv | Rattus norvegicus | 3 | ALA4020748 | organism-based format | Scientific Literature | |
| 11. | ALA4021703 | A | Fraction unbound in Wistar Hannover rat plasma | Rattus norvegicus | 1 | ALA4020748 | cell-free format | Scientific Literature | |
| 12. | ALA4021704 | A | Half life in Wistar Hannover rat at 2 mg/kg, iv | Rattus norvegicus | 3 | ALA4020748 | organism-based format | Scientific Literature | |
| 13. | ALA4021705 | A | Oral bioavailability in Wistar Hannover rat at 10 mg/kg | Rattus norvegicus | 3 | ALA4020748 | organism-based format | Scientific Literature | |
| 14. | ALA4021706 | P | Apparent permeability of the compound | 3 | ALA4020748 | small-molecule physicochemical format | Scientific Literature | ||
| 15. | ALA4021707 | F | Analgesic activity in C57BL/6 mouse assessed as reduction in formalin-induced nociceptive behavior at 100 mg/kg, sc pretreated for 90 mins followed by formalin challenge measured up to 5 mins | Mus musculus | 1 | ALA4020748 | organism-based format | Scientific Literature | |
| 16. | ALA4021709 | B | Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated electrophysiology method | Homo sapiens | 11 | ALA4020748 | cell-based format | Scientific Literature | |
| 17. | ALA4021710 | A | Activity at CYP450 (unknown origin) | Homo sapiens | 1 | ALA4020748 | assay format | Scientific Literature | |
| 18. | ALA4021711 | A | Inhibition of Nav1.2 (unknown origin) | Homo sapiens | 1 | ALA4020748 | single protein format | Scientific Literature | |
| 19. | ALA4021712 | F | Analgesic activity in C57BL/6 mouse assessed as reduction in formalin-induced nociceptive behavior at 100 mg/kg, sc pretreated for 90 mins followed by formalin challenge measured after 20 to 35 mins | Mus musculus | 2 | ALA4020748 | organism-based format | Scientific Literature | |
| 20. | ALA4021713 | A | Fraction unbound in C57BL/6 mouse plasma at 100 mg/kg, sc | Mus musculus | 2 | ALA4020748 | organism-based format | Scientific Literature |
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