# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA620892 | ADME | Area under the MAP curve measured over 5 min. | 10 | ALA1135780 | assay format | Scientific Literature | ||
2. | ALA626495 | ADME | Half life after oral tested | 1 | ALA1135780 | organism-based format | Scientific Literature | ||
3. | ALA626498 | ADME | Oral bioavailability after oral tested | 1 | ALA1135780 | organism-based format | Scientific Literature | ||
4. | ALA655070 | Functional | Changes in potassium fluxes assessed in the glucose responsive insulin-producing murine cell line beta-TC3 | Mus musculus | 30 | ALA1135780 | cell-based format | Scientific Literature | |
5. | ALA650713 | Functional | Percentage insulin release in vitro in beta-TC6 cells | Mus musculus | 10 | ALA1135780 | cell-based format | Scientific Literature | |
6. | ALA650714 | Functional | Ability to inhibit the release of insulin from the mouse beta-TC6 cell line | Mus musculus | 32 | ALA1135780 | cell-based format | Scientific Literature | |
7. | ALA866639 | Functional | Repolarization of beta-TC3 cells | Mus musculus | 20 | ALA1138902 | cell-based format | Scientific Literature | |
8. | ALA866796 | Functional | Inhibition of glucose-stimulated insulin release in betaTC6 cells | Mus musculus | 20 | ALA1138902 | cell-based format | Scientific Literature | |
9. | ALA866797 | Functional | Inhibition of glucose-stimulated insulin release in beta-TC6 cells at 10 uM | Mus musculus | 20 | ALA1138902 | cell-based format | Scientific Literature | |
10. | ALA866793 | Functional | Relaxation of precontracted Wistar rat aorta rings | Rattus norvegicus | 20 | ALA1138902 | organism-based format | Scientific Literature | |
11. | ALA810541 | Binding | Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high affinity state with 2 mM MgATP | Homo sapiens | 9 | ALA1135780 | cell-based format | Scientific Literature | |
12. | ALA810542 | Binding | Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low affinity state with 2 mM MgATP | Homo sapiens | 9 | ALA1135780 | cell-based format | Scientific Literature | |
13. | ALA810543 | Binding | Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without ATP | Homo sapiens | 8 | ALA1135780 | cell-based format | Scientific Literature | |
14. | ALA783708 | Functional | Inhibition of glucose-stimulated insulin release from Wistar rat islets | Rattus norvegicus | 10 | ALA1135780 | organism-based format | Scientific Literature | |
15. | ALA780694 | Functional | Ability to relax phenylephrine-contracted rat aorta rings | Rattus norvegicus | 31 | ALA1135780 | organism-based format | Scientific Literature | |
16. | ALA779272 | Functional | Vasodilation effects on Wistar rat mesenteric arteries precontracted with phenylephrine | Rattus norvegicus | 11 | ALA1135780 | organism-based format | Scientific Literature | |
17. | ALA795718 | Functional | Maximum reduction in plasma insulin in rat | Rattus norvegicus | 11 | ALA1135780 | organism-based format | Scientific Literature | |
18. | ALA794528 | Functional | Reduction in plasma insulin in 30 min post-injection in rat | Rattus norvegicus | 11 | ALA1135780 | organism-based format | Scientific Literature | |
19. | ALA779142 | Functional | Maximum change in MAP in rat | Rattus norvegicus | 11 | ALA1135780 | organism-based format | Scientific Literature |