| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4020470 | F | Antimicrobial activity against methicillin resistant Staphylococcus aureus ATCC 33591 after 16 hrs | Staphylococcus aureus | 26 | assay format | Scientific Literature | ||
| 2. | ALA4020471 | F | Antimicrobial activity against methicillin resistant Staphylococcus epidermidis RP62A after 16 hrs | Staphylococcus epidermidis | 26 | assay format | Scientific Literature | ||
| 3. | ALA4020472 | F | Antimicrobial activity against vancomycin resistant Enterococcus faecalis ATCC 700802 after 16 hrs | Enterococcus faecalis | 26 | assay format | Scientific Literature | ||
| 4. | ALA4020473 | F | Antimicrobial activity against Escherichia coli ATCC 25922 after 16 hrs | Escherichia coli | 26 | assay format | Scientific Literature | ||
| 5. | ALA4020474 | F | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after 16 hrs | Pseudomonas aeruginosa | 26 | assay format | Scientific Literature | ||
| 6. | ALA4020475 | F | Antimicrobial activity against Klebsiella pneumoniae ATCC 13383 after 16 hrs | Klebsiella pneumoniae | 26 | assay format | Scientific Literature | ||
| 7. | ALA4020476 | U | Retention time of compound by HPLC analysis | 10 | assay format | Scientific Literature | |||
| 8. | ALA4020477 | A | Cytotoxicity against human C13 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4020478 | A | Cytotoxicity against human HCT116 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4020480 | U | Selectivity index, ratio of HC50 for mouse RBC to MIC for methicillin resistance Staphylococcus aureus ATCC 33591 | 8 | assay format | Scientific Literature | |||
| 11. | ALA4020481 | F | Induction of membrane disruption in methicillin resistance Staphylococcus aureus ATCC 33591 at 5 ug/ml after 2 hrs by propidium iodide/4', 6'-diamidino-2-phenylindole dihydrochloride dye based fluorescence microscopy | Staphylococcus aureus | 1 | assay format | Scientific Literature | ||
| 12. | ALA4020482 | F | Induction of membrane disruption in Escherichia coli ATCC 25922 at 5 ug/ml after 2 hrs by propidium iodide/4', 6'-diamidino-2-phenylindole dihydrochloride dye based fluorescence microscopy | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 13. | ALA4020485 | F | Bactericidal activity against methicillin resistance Staphylococcus aureus ATCC 33591 at 25 ug/ml after 10 mins by time kill analysis | Staphylococcus aureus | 1 | assay format | Scientific Literature | ||
| 14. | ALA4020486 | F | Bactericidal activity against methicillin resistance Staphylococcus aureus ATCC 33591 at 2 ug/ml after 60 mins by time kill analysis | Staphylococcus aureus | 1 | assay format | Scientific Literature | ||
| 15. | ALA4020487 | F | Bactericidal activity against Escherichia coli ATCC 25922 at 25 to 50 ug/ml after 30 mins by time kill analysis | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 16. | ALA4020488 | F | Bactericidal activity against Escherichia coli ATCC 25922 at 4 ug/ml after 60 mins by time kill analysis | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 17. | ALA4020489 | F | Antibacterial activity against methicillin resistance Staphylococcus aureus ATCC 33591 after 14 serial passage at 0.5 times MIC after 16 hrs | Staphylococcus aureus | 1 | assay format | Scientific Literature | ||
| 18. | ALA4020490 | F | Antibacterial activity against methicillin resistance Staphylococcus aureus ATCC 33591 infected in Wistar rat assessed as reduction in bacterial load in bronchoalveolar lavage of lungs at 10 mg/kg, iv treated 24 hrs post infection measured after 3 days relative to control | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA4020491 | F | Antibacterial activity against methicillin resistance Staphylococcus aureus ATCC 33591 infected in Wistar rat assessed as reduction in bacterial load in bronchoalveolar lavage of lungs at 10 mg/kg, iv treated 24 hrs post infection measured after 5 days relative to control | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA4020492 | F | Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC 33591 infected in Wistar rat assessed as reduction in lung inflammation at 10 mg/kg, iv treated 24 hrs post infection measured after 5 days by hematoxylin/ eosin staining based microscopic analysis | Staphylococcus aureus | 2 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!